Polyvinylpyrrolidone (PVP) is a hydrophilic polymer widely employed as a carrier in the
pharmaceutical, biomedical, and nutraceutical fields. Up to now, several PVP-based …

Intracellular delivery is considered an indispensable process for various studies, ranging
from medical applications (cell‐based therapy) to fundamental (genome‐editing) and …

Within the field of gene therapy, there is a considerable need for the development of non-
viral vectors that are able to compete with the efficiency obtained by viral vectors, while …

Due to the potential use as transfecting agents of nucleic acids (DNA or RNA), multivalent
cationic non-viral vectors have received special attention in the last decade. Much effort has …

Efficient small interfering RNA (siRNA) delivery in the presence of serum is of crucial
importance for effective gene therapy. Fluorinated vectors are considered to be attractive …

Abstract Recently, electro-Fenton (EF) process has been shown as a promising, facile,
effective, low cost and environmentally-friendly alternative for synthesizing polymer …

The potential of gene therapy for the treatment for chronic and life-threatening diseases has
been seen for a long time, but widespread applications are still hampered by the difficulties …

Nanosized systems of DOX with antitumor activity on the base of micelle-like particles of
amphiphilic thermosensitive copolymers of N-vinylpyrrolidone (VP) with triethylene glycol …

Gene therapy is an auspicious alternative to treat diseases. However, the design of efficient
vectors remains as a challenge due to the innumerous intracellular and extracellular barriers …

Amphiphilic copolymers of N-vinylpyrrolidone and methacrylic acid, and triethylene glycol
dimethacrylate (branching agent) are synthesized by radical copolymerization in toluene …