[HTML][HTML] Extracellular matrix: a dynamic microenvironment for stem cell niche
F Gattazzo, A Urciuolo, P Bonaldo - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
Background Extracellular matrix (ECM) is a dynamic and complex environment
characterized by biophysical, mechanical and biochemical properties specific for each …
characterized by biophysical, mechanical and biochemical properties specific for each …
Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration
C Jopling, S Boue, JCI Belmonte - Nature reviews Molecular cell …, 2011 - nature.com
The ultimate goal of regenerative medicine is to replace lost or damaged cells. This can
potentially be accomplished using the processes of dedifferentiation, transdifferentiation or …
potentially be accomplished using the processes of dedifferentiation, transdifferentiation or …
Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment
Bone marrow mesenchymal lineage cells are a heterogeneous cell population involved in
bone homeostasis and diseases such as osteoporosis. While it is long postulated that they …
bone homeostasis and diseases such as osteoporosis. While it is long postulated that they …
Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance
K Ito, R Turcotte, J Cui, SE Zimmerman, S Pinho… - Science, 2016 - science.org
A single hematopoietic stem cell (HSC) is capable of reconstituting hematopoiesis and
maintaining homeostasis by balancing self-renewal and cell differentiation. The …
maintaining homeostasis by balancing self-renewal and cell differentiation. The …
[HTML][HTML] Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
A Wilson, E Laurenti, G Oser, RC van der Wath… - Cell, 2008 - cell.com
Bone marrow hematopoietic stem cells (HSCs) are crucial to maintain lifelong production of
all blood cells. Although HSCs divide infrequently, it is thought that the entire HSC pool turns …
all blood cells. Although HSCs divide infrequently, it is thought that the entire HSC pool turns …
IFNα activates dormant haematopoietic stem cells in vivo
MAG Essers, S Offner, WE Blanco-Bose, Z Waibler… - Nature, 2009 - nature.com
Maintenance of the blood system is dependent on dormant haematopoietic stem cells
(HSCs) with long-term self-renewal capacity. After injury these cells are induced to …
(HSCs) with long-term self-renewal capacity. After injury these cells are induced to …
Adipose tissue stem cells meet preadipocyte commitment: going back to the future [S]
White adipose tissue (WAT) is perhaps the most plastic organ in the body, capable of
regeneration following surgical removal and massive expansion or contraction in response …
regeneration following surgical removal and massive expansion or contraction in response …
Hematopoietic hierarchy–an updated roadmap
The classical roadmap of hematopoietic hierarchy has been proposed for nearly 20 years
and has become a dogma of stem cell research for most types of adult stem cells, including …
and has become a dogma of stem cell research for most types of adult stem cells, including …
[HTML][HTML] Cell cycle regulation in hematopoietic stem cells
EM Pietras, MR Warr, E Passegué - The Journal of cell biology, 2011 - ncbi.nlm.nih.gov
Hematopoietic stem cells (HSCs) give rise to all lineages of blood cells. Because HSCs must
persist for a lifetime, the balance between their proliferation and quiescence is carefully …
persist for a lifetime, the balance between their proliferation and quiescence is carefully …
[HTML][HTML] The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in
A Ehninger, A Trumpp - The Journal of experimental medicine, 2011 - ncbi.nlm.nih.gov
Stem cell niches are defined as the cellular and molecular microenvironments that regulate
stem cell function together with stem cell autonomous mechanisms. This includes control of …
stem cell function together with stem cell autonomous mechanisms. This includes control of …