Hereunder, we highlight bacterial membrane anionic lipids as attractive targets in the design
of antibacterial drugs which can be effective against both Gram-positive and Gram-negative …

Infectious diseases remain significant health concerns worldwide, and resistance is
particularly common in patients with tuberculosis caused by Mycobacterium tuberculosis …

Synergistic antibacterial activity of combined silver nanoparticles (AgNPs) with tetracycline
(polykeptide), neomycin (aminoglycoside), and penicillin (β-lactam) was tested against the …

Chicken Farmers of Canada has been progressively phasing out prophylactic use of
antibiotics in broiler chicken production. Consequently, hatcheries, veterinarians, and …

The relentless rise in antibiotic resistance among pathogenic bacteria and fungi, coupled
with the high susceptibility of burn wounds to infection, and the difficulty of systemically …

Despite their inherent toxicity and the acquired bacterial resistance that continuously
threaten their long-term clinical use, aminoglycosides (AGs) still remain valuable …

Amphiphilic aminoglycosides (AAGs) are an emerging source of antibacterials to combat
infections caused by antibiotic‐resistant bacteria. Mode‐of‐action studies indicate that AAGs …

Aminoglycosides (AGs) constitute a major family of potent and broad-spectrum antibiotics
disturbing protein synthesis through binding to the A site of 16S rRNA. Decades of …

The attachment of alkyl and other hydrophobic groups to traditional antibacterial kanamycins
and neomycins creates amphiphilic aminoglycosides with altered antimicrobial properties. In …

Aminoglycosides are antibiotic drugs that act through binding to rRNA. In the search for
antimicrobial amphiphilic aminoglycosides targeting bacterial membranes, we report here …