The objective of the present review was to summarize the molecular mechanisms
associated with the effects of the vitamins A, C, E and K, and group B vitamins on bone and …

Alkaline phosphatase (ALP) is an evolutionary conserved enzyme and widely used
biomarker in clinical practice. Tissue-nonspecific alkaline phosphatase (TNALP) is one of …

As human life expectancy is rising, the incidence of age-associated diseases will also
increase. Scientific evidence has revealed that healthy diets, including good fats, vitamins …

Bone is a metabolically active tissue that renews itself throughout one's life. Cytokines along
with several hormonal, nutritional, and growth factors are involved in tightly regulated bone …

Vitamin K acts as a coenzyme of carboxylase, catalyzing the carboxylation of several vitamin
K dependent proteins. Beyond its well-known effects on blood coagulation, it also exerts …

We have investigated whether low-dose vitamin K2 supplements (menaquinone-7, MK-7)
could beneficially affect bone health. Next to an improved vitamin K status, MK-7 …

In contrast to other fat-soluble vitamins, dietary vitamin K is rapidly lost to the body resulting
in comparatively low tissue stores. Deficiency is kept at bay by the ubiquity of vitamin K in the …

Although it has long been recognized that inflammation, a consequence of immune‐driven
processes, significantly impacts bone turnover, the degree of centralization of skeletal and …

Vitamin K is a liposoluble vitamin. The predominant dietary form, phylloquinone or vitamin
K1, is found in plants and green vegetables; whereas menaquinone, or vitamin K2, is …

Bone is a dynamic tissue that undergoes renewal throughout life in a process whereby
osteoclasts resorb worn bone and osteoblasts synthesize new bone. Imbalances in bone …