The hematologic consequences of obesity

JC Purdy, JJ Shatzel - European journal of haematology, 2021 - Wiley Online Library
The prevalence of obesity is increasing and progressively influencing physician‐patient
interactions. While there is a sizable amount of data demonstrating that obesity is a state of …

[HTML][HTML] Procedure, applications, and outcomes of autologous fat grafting

F Simonacci, N Bertozzi, MP Grieco… - Annals of medicine and …, 2017 - Elsevier
Objective To systematically review the procedure, applications, and outcomes of autologous
fat grafting, a promising technique with various clinical applications. Patients and methods …

Adipose tissue macrophages: going off track during obesity

L Boutens, R Stienstra - Diabetologia, 2016 - Springer
Inflammation originating from the adipose tissue is considered to be one of the main driving
forces for the development of insulin resistance and type 2 diabetes in obese individuals …

[HTML][HTML] Mechanisms and metabolic implications of regional differences among fat depots

T Tchkonia, T Thomou, YI Zhu, I Karagiannides… - Cell metabolism, 2013 - cell.com
Fat distribution is closely linked to metabolic disease risk. Distribution varies with sex,
genetic background, disease state, certain drugs and hormones, development, and aging …

Dietary factors and low-grade inflammation in relation to overweight and obesity

PC Calder, N Ahluwalia, F Brouns, T Buetler… - British Journal of …, 2011 - cambridge.org
Low-grade inflammation is a characteristic of the obese state, and adipose tissue releases
many inflammatory mediators. The source of these mediators within adipose tissue is not …

[HTML][HTML] Linking chronic inflammation with cardiovascular disease: from normal aging to the metabolic syndrome

A Lopez-Candales, PMH Burgos… - Journal of nature and …, 2017 - ncbi.nlm.nih.gov
The metabolic syndrome (MetS) is a cluster of clinical disorders including an unhealthy body
habitus with a large waistline, dyslipidemia, glucose intolerance and hypertension. It is …

Fat tissue, aging, and cellular senescence

T Tchkonia, DE Morbeck, T Von Zglinicki… - Aging cell, 2010 - Wiley Online Library
Fat tissue, frequently the largest organ in humans, is at the nexus of mechanisms involved in
longevity and age‐related metabolic dysfunction. Fat distribution and function change …

Adipocyte-macrophage cross-talk in obesity

AB Engin - Obesity and lipotoxicity, 2017 - Springer
Obesity is characterized by the chronic low-grade activation of the innate immune system. In
this respect, macrophage-elicited metabolic inflammation and adipocyte-macrophage …

Characterization of the adipocyte cellular lineage in vivo

R Berry, MS Rodeheffer - Nature cell biology, 2013 - nature.com
Mature adipocytes are generated through the proliferation and differentiation of precursor
cells. Our previous studies identified adipocyte progenitors in white adipose tissue (WAT) as …

[HTML][HTML] Obesity is associated with macrophage accumulation in adipose tissue

SP Weisberg, D McCann, M Desai… - The Journal of …, 2003 - Am Soc Clin Investig
Obesity alters adipose tissue metabolic and endocrine function and leads to an increased
release of fatty acids, hormones, and proinflammatory molecules that contribute to obesity …