QSAR, molecular docking and ADMET studies of quinoline, isoquinoline and quinazoline derivatives against Plasmodium falciparum malaria
With the aim of researching new antimalarial drugs, a series of quinoline, isoquinoline, and
quinazoline derivatives were studied against the Plasmodium falciparum CQ-sensitive and …
quinazoline derivatives were studied against the Plasmodium falciparum CQ-sensitive and …
Discovery of dual-target natural antimalarial agents against DHODH and PMT of Plasmodium falciparum: pharmacophore modelling, molecular docking, quantum …
EM Elamin, SE Eshage, SM Mohmmode… - SAR and QSAR in …, 2023 - Taylor & Francis
Malaria is a lethal disease that claims thousands of lives worldwide annually. The objective
of this study was to identify new natural compounds that can target two P. falciparum …
of this study was to identify new natural compounds that can target two P. falciparum …
A hyperthermoactive-Cas9 editing tool reveals the role of a unique arsenite methyltransferase in the arsenic resistance system of Thermus thermophilus HB27
G Gallo, I Mougiakos, M Bianco, M Carbonaro… - MBio, 2021 - Am Soc Microbiol
Arsenic detoxification systems can be found in a wide range of organisms, from bacteria to
humans. In a previous study, we discovered an arsenic-responsive transcriptional regulator …
humans. In a previous study, we discovered an arsenic-responsive transcriptional regulator …
[HTML][HTML] Progress and challenges in the use of fluorescence‐based flow cytometric assays for anti‐malarial drug susceptibility tests
K Kulkeaw - Malaria Journal, 2021 - Springer
Drug-resistant Plasmodium is a frequent global threat in malaria eradication programmes,
highlighting the need for new anti-malarial drugs and efficient detection of treatment failure …
highlighting the need for new anti-malarial drugs and efficient detection of treatment failure …
QSAR, molecular docking and ADMET studies of Quinoline, Isoquinoline and Quinazoline derivatives against Plasmodium falciparum malaria
ELR Said, C Samir, K Fouad - 2022 - researchsquare.com
With the aim of researching new antimalarial drugs, a series of quinoline, isoquinoline and
quinazoline derivatives were studied against the Plasmodium falciparum CQ-sensitive and …
quinazoline derivatives were studied against the Plasmodium falciparum CQ-sensitive and …
Development of selective Inhibitors of crucial drug target Phosphoethanolamine methyltransferase of Plasmodium falciparum based on Chemo informatics and in vitro …
The chemo informatics and simulation approaches are highly preferred to develop drug
candidate, applied in the study to develop a combinatorial library to meet, the need of new …
candidate, applied in the study to develop a combinatorial library to meet, the need of new …