Alzheimer's disease (AD) is one of the biggest human health threats due to increases in
aging of the global population. Unfortunately, drugs for treating AD have been largely …

Different studies corroborate a role for ceramide synthases and their downstream products,
ceramides, in modulation of apoptosis and autophagy in the context of cancer. These …

Cytochrome P450 and other families of drug-metabolizing enzymes are commonly thought
of and studied for their ability to metabolize xenobiotics and other foreign entities as they are …

Complications in the etiology of Alzheimer Disease (AD) as being a concern among the
research scientist and medicinal community. Hybrids compounds with multi-targeted …

Simultaneous inhibition of soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase
(FAAH) with a single small molecule represents a novel therapeutic approach in treating …

Cyclooxygenase and lipoxygenase derived lipid metabolites of polyunsaturated fatty acids
(PUFAs), as well as their role in the inflammation, have been studied quite thoroughly …

Soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH) are potential
targets for several diseases. Previous studies have reported that concomitant selective …

Il sistema endocannabinoide (SEC), una rete neuronale diffusa, contribuisce attivamente
allo sviluppo del sistema nervoso centrale (SNC), regolando diversi processi cognitivi e …

Chronic pain is the most common reason to seek medical attention, yet many long-term
treatments for pain produce both dangerous and unpleasant side effects. New treatments …

Bu tezde, lipopolisakkarit (LPS) ile farelerde oluşturulan enflamatuvar hiperaljezi modelinde
çözünebilir epoksit hidrolaz (çEH) inhibisyonunun etkisinin mekanizmasının pro …