Visible-light optical coherence tomography: a review
Visible-light optical coherence tomography (vis-OCT) is an emerging imaging modality,
providing new capabilities in both anatomical and functional imaging of biological tissue. It …
providing new capabilities in both anatomical and functional imaging of biological tissue. It …
[HTML][HTML] Noninvasive hemoglobin sensing and imaging: optical tools for disease diagnosis
Significance: Measurement and imaging of hemoglobin oxygenation are used extensively in
the detection and diagnosis of disease; however, the applied instruments vary widely in their …
the detection and diagnosis of disease; however, the applied instruments vary widely in their …
[HTML][HTML] High-resolution functional photoacoustic monitoring of vascular dynamics in human fingers
Functional imaging of microvascular dynamics in extremities delivers intuitive information for
early detection, diagnosis, and prognosis of vascular diseases. High-resolution and high …
early detection, diagnosis, and prognosis of vascular diseases. High-resolution and high …
Functional and oxygen-metabolic photoacoustic microscopy of the awake mouse brain
A long-standing challenge in optical neuroimaging has been the assessment of
hemodynamics and oxygen metabolism in the awake rodent brain at the microscopic level …
hemodynamics and oxygen metabolism in the awake rodent brain at the microscopic level …
More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction
Our understanding of how capillary blood flow and oxygen distribute across cortical layers to
meet the local metabolic demand is incomplete. We addressed this question by using two …
meet the local metabolic demand is incomplete. We addressed this question by using two …
Neurophotonic tools for microscopic measurements and manipulation: status report
Neurophotonics was launched in 2014 coinciding with the launch of the BRAIN Initiative
focused on development of technologies for advancement of neuroscience. For the last …
focused on development of technologies for advancement of neuroscience. For the last …
Compromised microvascular oxygen delivery increases brain tissue vulnerability with age
Despite the possible role of impaired cerebral tissue oxygenation in age-related cognition
decline, much is still unknown about the changes in brain tissue pO2 with age. Using a …
decline, much is still unknown about the changes in brain tissue pO2 with age. Using a …
Modeling of Cerebral Oxygen Transport Based on In vivo Microscopic Imaging of Microvascular Network Structure, Blood Flow, and Oxygenation
Oxygen is delivered to brain tissue by a dense network of microvessels, which actively
control cerebral blood flow (CBF) through vasodilation and contraction in response to …
control cerebral blood flow (CBF) through vasodilation and contraction in response to …
The development and clinical application of innovative optical ophthalmic imaging techniques
P Alexopoulos, C Madu, G Wollstein… - Frontiers in …, 2022 - frontiersin.org
The field of ophthalmic imaging has grown substantially over the last years. Massive
improvements in image processing and computer hardware have allowed the emergence of …
improvements in image processing and computer hardware have allowed the emergence of …
[HTML][HTML] Direct measurement of neuronal ensemble activity using photoacoustic imaging in the stimulated Fos-LacZ transgenic rat brain: A proof-of-principle study
JI Matchynski, R Manwar, KJ Kratkiewicz… - Photoacoustics, 2021 - Elsevier
Measuring neuroactivity underlying complex behaviors facilitates understanding the
microcircuitry that supports these behaviors. We have developed a functional and molecular …
microcircuitry that supports these behaviors. We have developed a functional and molecular …