Adeno-associated viral vectors (AAVs) have become popular for gene therapy, given their
many advantages, including their reduced inflammatory profile compared with that of other …

Implantable devices with desirable biocompatibility and even degradability are of significant
interest to biomedical communities. Biologically safe and resorbable electronic materials …

Circadian clocks are a near-ubiquitous feature of biology, allowing organisms to optimise
their physiology to make the most efficient use of resources and adjust behaviour to …

Advanced age-related macular degeneration (AMD), the leading cause of blindness among
people over 50 years of age, is characterized by atrophic neurodegeneration or pathologic …

Vision is a highly rhythmic function adapted to the extensive changes in light intensity
occurring over the 24-hour day. This adaptation relies on rhythms in cellular and molecular …

Lamin B1 and lamin B2 are essential building blocks of the nuclear lamina, a filamentous
meshwork lining the nucleoplasmic side of the inner nuclear membrane. Deficiencies in …

Melatonin is an important player in the regulation of many physiological functions within the
body and in the retina. Melatonin synthesis in the retina primarily occurs during the night and …

Non-alcoholic fatty liver disease (NAFLD) is associated with obesity, insulin resistance, type
2 diabetes and cardiovascular disease and can be considered the hepatic manifestation of …

The development of new treatments for intractable retinal diseases requires reliable
functional assessment tools for animal models. In vivo measurements of neural activity …

Circadian clocks predictively adjust the physiology of organisms to the day/night cycle. The
retina has its own clock, and many diurnal changes in its physiology have been reported …