Proteoglycans in articular cartilage and their contribution to chondral injury and repair mechanisms
L Alcaide-Ruggiero, R Cugat… - International journal of …, 2023 - mdpi.com
Proteoglycans are vital components of the extracellular matrix in articular cartilage, providing
biomechanical properties crucial for its proper functioning. They are key players in chondral …
biomechanical properties crucial for its proper functioning. They are key players in chondral …
Platelet‐rich plasma injections induce disease‐modifying effects in the treatment of osteoarthritis in animal models
A Boffa, M Salerno, G Merli… - Knee Surgery …, 2021 - Wiley Online Library
Purpose The mechanisms of action and disease‐modifying potential of platelet‐rich plasma
(PRP) injection for osteoarthritis (OA) treatment are still not fully established. The aim of this …
(PRP) injection for osteoarthritis (OA) treatment are still not fully established. The aim of this …
Microfragmented adipose tissue versus platelet-rich plasma for the treatment of knee osteoarthritis: a prospective randomized controlled trial at 2-year follow-up
S Zaffagnini, L Andriolo, A Boffa… - … American Journal of …, 2022 - journals.sagepub.com
Background: Intra-articular microfragmented adipose tissue (MF-AT) injections have been
proposed for the treatment of knee osteoarthritis (OA). Purpose: To compare a single …
proposed for the treatment of knee osteoarthritis (OA). Purpose: To compare a single …
Role of adipose tissues in osteoarthritis
N Zapata-Linares, F Eymard… - Current Opinion in …, 2021 - journals.lww.com
The recent description of adipose tissues of various phenotypes within an osteoarthritic joint
allows us to evoke their direct involvement in the initiation and progression of the …
allows us to evoke their direct involvement in the initiation and progression of the …
Infrared thermography in symptomatic knee osteoarthritis: joint temperature differs based on patient and pain characteristics
L De Marziani, A Boffa, L Angelelli, L Andriolo… - Journal of Clinical …, 2023 - mdpi.com
The aim of this study was to evaluate osteoarthritis (OA) patients with infrared thermography
to investigate imaging patterns as well as demographic and clinical characteristics that …
to investigate imaging patterns as well as demographic and clinical characteristics that …
Inhibition of TRADD ameliorates chondrocyte necroptosis and osteoarthritis by blocking RIPK1-TAK1 pathway and restoring autophagy
K Sun, Z Guo, J Zhang, L Hou, S Liang, F Lu… - Cell Death …, 2023 - nature.com
Osteoarthritis (OA) is an age-related disease characterized by cartilage degeneration.
TNFR1-associated death domain protein (TRADD) is a key upstream molecule of TNF-α …
TNFR1-associated death domain protein (TRADD) is a key upstream molecule of TNF-α …
Changes in the synovial fluid cytokine profile of the knee between an acute anterior cruciate ligament injury and surgical reconstruction
MT Kingery, U Anil, EJ Berlinberg… - … American Journal of …, 2022 - journals.sagepub.com
Background: Changes in the intra-articular inflammatory state during the immediate period
after an acute anterior cruciate ligament (ACL) rupture are not well defined. Purpose: To …
after an acute anterior cruciate ligament (ACL) rupture are not well defined. Purpose: To …
Inflammation-driven secretion potential is upregulated in osteoarthritic fibroblast-like synoviocytes
J Chwastek, M Kędziora, M Borczyk… - International Journal of …, 2022 - mdpi.com
Osteoarthritis (OA) is one of the most common joint pathologies and a major cause of
disability among the population of developed countries. It manifests as a gradual …
disability among the population of developed countries. It manifests as a gradual …
Healthy and osteoarthritis-affected joints facing the cellular crosstalk
S Semenistaja, S Skuja, A Kadisa, V Groma - International Journal of …, 2023 - mdpi.com
Osteoarthritis (OA) is a chronic, progressive, severely debilitating, and multifactorial joint
disease that is recognized as the most common type of arthritis. During the last decade, it …
disease that is recognized as the most common type of arthritis. During the last decade, it …
Effects of platelet-rich plasma on subchondral bone marrow edema and biomarkers in synovial fluid of knee osteoarthritis
W Lin, L Xie, L Zhou, J Zheng, W Zhai, D Lin - The Knee, 2023 - Elsevier
Background The aim of the study was to investigate the effect of platelet-rich plasma (PRP)
on subchondral bone marrow edema (BME) and the level of biomarkers in synovial fluid of …
on subchondral bone marrow edema (BME) and the level of biomarkers in synovial fluid of …