A nanotechnology-based approach to biosensor application in current diabetes management practices

A Shoaib, A Darraj, ME Khan, L Azmi, A Alalwan… - Nanomaterials, 2023 - mdpi.com
Diabetes mellitus is linked to both short-term and long-term health problems. Therefore, its
detection at a very basic stage is of utmost importance. Research institutes and medical …

A review on efforts for improvement in medicinally important chemical constituents inAconitum through biotechnological interventions

S Tiwari, P Acharya, B Solanki, AK Sharma, S Rawat - 3 Biotech, 2023 - Springer
The genus Aconitum belongs to the family Ranunculaceae, is endowed with more than 350
species on the earth. Medicinally important aconitine type of diterpenoid alkaloids are the …

Assessment of antidiabetic activity of the shikonin by allosteric inhibition of protein-tyrosine phosphatase 1B (PTP1B) using state of art: an in silico and in vitro tactics

M Saeed, A Shoaib, M Tasleem, NM Alabdallah… - Molecules, 2021 - mdpi.com
Diabetes mellitus is a multifactorial disease that affects both developing and developed
countries and is a major public health concern. Many synthetic drugs are available in the …

Role of Alkannin in the Therapeutic Targeting of Protein-Tyrosine Phosphatase 1B and Aldose Reductase in Type 2 Diabetes: An In Silico and In Vitro Evaluation

M Saeed, A Shoaib, M Tasleem, A Al-Shammary… - ACS …, 2024 - ACS Publications
Alkannin is a plant-derived naphthoquinone that is isolated from the Boraginaceae family
plants. In our previous studies, we found that shikonin, which is the R-enantiomer of …

[HTML][HTML] Investigation of antidiabetic properties of shikonin by targeting aldose reductase enzyme: In silico and in vitro studies

M Saeed, M Tasleem, A Shoaib, NM Alabdallah… - Biomedicine & …, 2022 - Elsevier
Diabetes is a complicated multifactorial disorder in which the patient generally observes
polyphagia, polydipsia, and polyuria due to uncontrolled growth in blood sugar levels. For its …

Effect of thymoquinone on high fat diet and STZ‐induced experimental type 2 diabetes: A mechanistic insight by in vivo and in silico studies

S Alshahrani, T Anwer, MF Alam… - Journal of Food …, 2021 - Wiley Online Library
The aim was to investigate whether thymoquinone (TQ) attenuates hyperglycemia‐induced
insulin resistance in experimental type 2 diabetes. Type 2 diabetes mellitus (T2DM) was …

[HTML][HTML] Physicochemical characterization, phytochemical analysis, and pharmacological evaluation of Sambucus wightiana

IA Chashoo, SUD Wani, WY Raja, ZA Bhat, M Ali… - Arabian Journal of …, 2023 - Elsevier
Sambucus wightiana (SW) is a 4–5-foot herbaceous stem with 5–9 leaflets and pinnatifid
leaves (15–30 cm). It is used to treat stomach disorders, as an emetic for expelling …

The known, unknown, and the intriguing about members of a critically endangered traditional medicinal plant genus Aconitum

RA Kakkar, MA Haneen, AC Parida… - Frontiers in Plant …, 2023 - frontiersin.org
Humanity will always be indebted to plants. In the ongoing scientific era, the 'Herbal
Revolution'has helped discover several valuable medicinal plants and associated novel …

Imidazole‐thiadiazole hybrids: A multitarget de novo drug design approach, in vitro evaluation, ADME/T, and in silico studies

M Maqbool, M Solangi, KM Khan, M Özil… - Archiv der …, 2024 - Wiley Online Library
A library of imidazole‐thiadiazole compounds (1–24) was synthesized to explore their
therapeutic applications. The compounds were subjected to meticulous in vitro evaluation …

Anti-Obesity Action of Boerhavia diffusa in Rats against High-Fat Diet-Induced Obesity by Blocking the Cannabinoid Receptors

M Khalid, MH Alqarni, A Shoaib, S Wahab, AI Foudah… - Plants, 2022 - mdpi.com
Obesity, type 2 diabetes, and cardiovascular illnesses have known risk factors in the
pathophysiology of an unhealthy diet. Obesity now affects almost a third of the world's …