The inorganic polymer, polyphosphate, blocks binding of SARS-CoV-2 spike protein to ACE2 receptor at physiological concentrations

M Neufurth, X Wang, E Tolba, I Lieberwirth… - Biochemical …, 2020 - Elsevier
Inorganic polyphosphate (polyP) is a morphogenetically active and metabolic energy-
delivering physiological polymer that is released from blood platelets. Here, we show that …

Development and simulation of fully glycosylated molecular models of ACE2-Fc fusion proteins and their interaction with the SARS-CoV-2 spike protein binding …

A Bernardi, Y Huang, B Harris, Y Xiong, S Nandi… - PLoS …, 2020 - journals.plos.org
We develop fully glycosylated computational models of ACE2-Fc fusion proteins which are
promising targets for a COVID-19 therapeutic. These models are tested in their interaction …

Impact of obesity and SARS-CoV-2 infection: implications for host defence-a living review

FC Richter, A Alrubayyi, A Teijeira Crespo… - Oxford Open …, 2021 - academic.oup.com
The role of obesity in the pathophysiology of respiratory virus infections has become
particularly apparent during the current severe acute respiratory syndrome coronavirus 2 …

[PDF][PDF] Development and simulation of fully glycosylated molecular models of ACE2-Fc fusion

A Bernardi, Y Huang, B Harris - 2020 - scholar.archive.org
We develop fully glycosylated computational models of ACE2-Fc fusion proteins which are
promising targets for a COVID-19 therapeutic. These models are tested in their interaction …