Abstract Purpose of Review Epigenetic modifications via DNA methylation have previously
been linked to blood lipid levels, dyslipidemias, and atherosclerosis. The purpose of this …

Abstract Purpose of Review An abnormal lipid profile is considered a main risk factor for
cardiovascular diseases and evidence suggests that single nucleotide polymorphisms …

With very large sample sizes, biobanks provide an exciting opportunity to identify genetic
components of complex traits. To analyze rare variants, region-based multiple-variant …

Abstract The APOE 2/3/4 polymorphism is the greatest genetic risk factor for Alzheimer's
disease (AD). This polymorphism is also associated with variation in plasma ApoE level; …

Most genome-wide association studies (GWAS) for lipid traits focus on the separate analysis
of lipid traits. Moreover, there are limited GWASs evaluating the genetic variants associated …

Importance The balance between the potential long-term clinical benefits and harms
associated with genetic cholesteryl ester transfer protein (CETP) deficiency, mimicking …

Genetic associations for lipid traits have identified hundreds of variants with clear differences
across European, Asian and African studies. Based on a sub-Saharan-African GWAS for …

Abstract Background Cardiovascular diseases (CVDs) comprise major causes of death
worldwide, leading to extensive burden on populations and societies. Alterations in normal …

Aims Study aimed to investigate the genetic correlations and potential causal relationships
between obstructive sleep apnoea (OSA) and various cardiovascular diseases (CVDs) …

Abnormalities in lipid metabolism have been linked to the development of obesity. We used
a nutrigenetic approach to establish a link between lipids and obesity in Asian Indians, who …