Alkene ozonolysis

TJ Fisher, PH Dussault - Tetrahedron, 2017 - Elsevier
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Isolation, chemical, and biotransformation routes of labdane-type diterpenes

LMT Frija, RFM Frade, CAM Afonso - Chemical reviews, 2011 - ACS Publications
Small molecule natural products continue to provide an incomparable source of inspiration
for advances in organic chemistry and disease treatment. 1Ā6 Labdane-type diterpenes are …

Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea(L.) and their relevance for perfume manufacture

A Caniard, P Zerbe, S Legrand, A Cohade, N Valot… - BMC plant biology, 2012 - Springer
Background Sclareol is a diterpene natural product of high value for the fragrance industry.
Its labdane carbon skeleton and its two hydroxyl groups also make it a valued starting …

Characterization of two genes for the biosynthesis of the labdane diterpene Z‐abienol in tobacco (Nicotiana tabacum) glandular trichomes

C Sallaud, C Giacalone, R Töpfer, S Goepfert… - The Plant …, 2012 - Wiley Online Library
Leaves of tobacco (Nicotiana tabacum) are covered with glandular trichomes that produce
sucrose esters and diterpenoids in varying quantities, depending on cultivar type. The …

Synthesis and Applications of Periodate for Fine Chemicals and Important Pharmaceuticals

S Arndt, PJ Kohlpaintner, K Donsbach… - … Process Research & …, 2022 - ACS Publications
An emerging interest for the application of periodate in the synthesis of active
pharmaceutical ingredients (APIs) and for the valorization of renewable feedstock is …

Efficient diterpene production in yeast by engineering Erg20p into a geranylgeranyl diphosphate synthase

C Ignea, FA Trikka, AK Nikolaidis, P Georgantea… - Metabolic …, 2015 - Elsevier
Terpenes have numerous applications, ranging from pharmaceuticals to fragrances and
biofuels. With increasing interest in producing terpenes sustainably and economically, there …

Enantio-and diastereoselective stepwise cyclization of polyprenoids induced by chiral and achiral LBAs. A new entry to (−)-Ambrox,(+)-Podocarpa-8, 11, 13-triene …

K Ishihara, H Ishibashi… - Journal of the American …, 2002 - ACS Publications
An enantio-and diastereoselective stepwise cyclization of polyprenoids induced by Lewis
acid-assisted chiral Brønsted acids (chiral LBAs) and achiral LBAs is described. In particular …

Developing an efficient and visible prime editing system to restore tobacco 8-hydroxy-copalyl diphosphate gene for labdane diterpene Z-abienol biosynthesis

J Zhang, L Zhang, C Zhang, Y Yang, H Liu, L Li… - Science China Life …, 2023 - Springer
Prime editing (PE) is a versatile CRISPR-Cas based precise genome-editing platform widely
used to introduce a range of possible base conversions in various organisms. However, no …

Bifunctional cis-abienol synthase from Abies balsamea discovered by transcriptome sequencing and its implications for diterpenoid fragrance production

P Zerbe, A Chiang, M Yuen, B Hamberger… - Journal of Biological …, 2012 - ASBMB
The labdanoid diterpene alcohol cis-abienol is a major component of the aromatic oleoresin
of balsam fir (Abies balsamea) and serves as a valuable bioproduct material for the …

[HTML][HTML] Reconstructing the chemical diversity of labdane-type diterpene biosynthesis in yeast

C Ignea, E Ioannou, P Georgantea, S Loupassaki… - Metabolic …, 2015 - Elsevier
Terpenes are a large class of natural products, many of which are used in cosmetics,
pharmaceuticals, or biofuels. However, terpene׳ s industrial application is frequently …