Many chronic diseases are marked by fibrosis, which is defined by an abundance of
activated fibroblasts and excessive deposition of extracellular matrix, resulting in loss of …

Stem cells (SCs) have evolved as an interesting and viable factor in ophthalmologic patient
care in the past decades. SCs have been classified as either embryonic, mesenchymal …

Background Glaucoma is a blinding degenerative neuropathy in which the death of retinal
ganglion cells (RGCs) causes progressive loss of visual field and eventually vision …

Carious lesions are bacteria-caused destructions of the mineralised dental tissues, marked
by the simultaneous activation of immune responses and regenerative events within the soft …

Background Smooth muscle cell (SMC) phenotype switching plays a central role during
vascular remodeling. Growth factor receptors are negatively regulated by protein tyrosine …

Purpose: We compared intravitreal injection of human adipose stem cell concentrated
conditioned media (ASC-CCM) to injection of live ASCs for their long-term safety and …

The carious lesion is a bacteria caused destruction of tooth mineralized matrices marked by
concurrent tissue reparative and immune responses in the dental pulp. While major …

Single-cell transcriptomes and multiomics studies from normal, injured, and diseased
arteries show that vascular smooth muscle cells (VSMCs) arise from multiple types of …