Objective Bariatric surgery is recommended for patients with obesity and type 2 diabetes.
Recent evidence suggested a strong connection between gut microbiota and bariatric …

Bile acids have important roles in the regulation of lipid, glucose and energy metabolism.
Metabolic diseases linked to obesity, including type 2 diabetes mellitus and non-alcoholic …

Objective Vertical sleeve gastrectomy (VSG) produces high rates of type 2 diabetes
remission; however, the mechanisms responsible remain incompletely defined. VSG …

Roux-en-Y gastric bypass (RYGB) is highly effective in reversing obesity and associated
diabetes. Recent observations in humans suggest a contributing role of increased …

Bile acids are increasingly recognized as key regulators of systemic metabolism. While bile
acids have long been known to play important and direct roles in nutrient absorption, bile …

Bile acids (BAs) are a family of hydroxylated steroids secreted by the liver that aid in the
breakdown and absorption of dietary fats. BAs also function as nutrient and inflammatory …

Chronic diseases, such as obesity and diabetes, cardiovascular, and inflammatory bowel
diseases (IBD) share common features in their pathology. Metabolic disorders exhibit strong …

Bile acids regulate nutrient absorption and mitochondrial function, they establish and
maintain gut microbial community composition and mediate inflammation, and they serve as …

Clinical studies have indicated that circulating bile acid (BA) concentrations increase
following bariatric surgery, especially following malabsorptive procedures such as Roux-en …

Bariatric surgery is currently the most effective treatment for obesity. Not only do these types
of surgeries produce significant weight loss but also they improve insulin sensitivity and …