Synonymous variants: necessary nuance in our understanding of cancer drivers and treatment outcomes
NM Kaissarian, D Meyer… - Journal Of The National …, 2022 - academic.oup.com
Once called “silent mutations” and assumed to have no effect on protein structure and
function, synonymous variants are now recognized to be drivers for some cancers. There …
function, synonymous variants are now recognized to be drivers for some cancers. There …
Next‐generation sequencing identifies novel single nucleotide polymorphisms in high‐risk cutaneous squamous cell carcinoma: A pilot study
MB Lobl, B Hass, D Clarey, S Higgins… - Experimental …, 2020 - Wiley Online Library
Background Cutaneous squamous cell carcinoma (SCC) causes 1 million cases in the
United States annually. There are germline single nucleotide polymorphisms (SNPs) that …
United States annually. There are germline single nucleotide polymorphisms (SNPs) that …
[HTML][HTML] Characterization of Asciminib-Resistant Philadelphia Chromosome-Positive Cells
S Okabe, M Moriyama, A Gotoh - World Journal of Oncology, 2024 - ncbi.nlm.nih.gov
Background Asciminib is approved for treating patients with chronic-phase chronic myeloid
leukemia who were previously treated with two or more tyrosine kinase inhibitors or those …
leukemia who were previously treated with two or more tyrosine kinase inhibitors or those …
[HTML][HTML] Natural killer cells expanded and preactivated exhibit enhanced antitumor activity against different tumor cells in vitro
One of the emerging treatment strategies for cancer particularly for haematological
malignancies is natural killer (NK) cell therapy. However, the availability of a best approach …
malignancies is natural killer (NK) cell therapy. However, the availability of a best approach …
[PDF][PDF] The role of HRAS rs12628 polymorphism in cancer risks: Evidence from a meta-analysis of 19 case-control studies
Y Wang, W Gao, Y Guo, C Peng - Int J Clin Exp Med, 2017 - e-century.us
There was inconsistent conclusion on the association between rs12628 polymorphism of
HRAS gene and human cancer risks. Therefore, we systematically carried out an updated …
HRAS gene and human cancer risks. Therefore, we systematically carried out an updated …
Prevalence of Abelson murine leukemia viral oncogene homolog-breakpoint cluster region fusions and correlation with peripheral blood parameters in chronic …
AA Kiani, F Shahsavar, M Gorji, K Ahmadi… - … Journal of Applied …, 2016 - journals.lww.com
Aims: In this study, patients with CML morphology were studied according to ABL-BCR
fusions and the relationship between the fusions and peripheral blood cell changes was …
fusions and the relationship between the fusions and peripheral blood cell changes was …
Insights into Cutaneous Squamous Cell Carcinoma Pathogenesis and Metastasis Using a Bedside-to-Bench Approach
M Lobl - 2021 - digitalcommons.unmc.edu
Cutaneous squamous cell carcinoma (SCC) is the second most common skin cancer,
affecting 1,000,000 people in the United States annually and causing approximately 9,000 …
affecting 1,000,000 people in the United States annually and causing approximately 9,000 …