Covering: up to June 2020 Ribosomally-synthesized and post-translationally modified
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …

The crisis of antibiotic resistance necessitates creative and innovative approaches, from
chemical identification and analysis to the assessment of bioactivity. Plant natural products …

Microorganisms produce small bioactive compounds as part of their secondary or
specialised metabolism. Often, such metabolites have antimicrobial, anticancer, antifungal …

Many microorganisms produce natural products that form the basis of antimicrobials,
antivirals, and other drugs. Genome mining is routinely used to complement screening …

Secondary metabolites produced by bacteria and fungi are an important source of
antimicrobials and other bioactive compounds. In recent years, genome mining has seen …

One of the exciting movements in microbial sciences has been a refocusing and
revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …

Complex microbial communities shape the dynamics of various environments, ranging from
the mammalian gastrointestinal tract to the soil. Advances in DNA sequencing technologies …

Microbial symbioses can mitigate drought stress in crops but harnessing these beneficial
interactions will require an in-depth understanding of root microbiome responses to drought …

Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a promising
source of new antimicrobials in the face of rising antibiotic resistance. Here, we report a …

Genome mining has become a key technology to exploit natural product diversity. Although
initially performed on a single-genome basis, the process is now being scaled up to mine …