Early life stress and development: potential mechanisms for adverse outcomes
Background Chronic and/or extreme stress in early life, often referred to as early adversity,
childhood trauma, or early life stress, has been associated with a wide range of adverse …
childhood trauma, or early life stress, has been associated with a wide range of adverse …
Emotion regulation as a transdiagnostic factor in the development of internalizing and externalizing psychopathology: Current and future directions
In response to rapidly growing rates of comorbidity among psychiatric disorders, clinical
scientists have become interested in identifying transdiagnostic processes that can help …
scientists have become interested in identifying transdiagnostic processes that can help …
Rethinking concepts and categories for understanding the neurodevelopmental effects of childhood adversity
Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for developing …
nervous-system development, health, and behavior is critically important for developing …
Childhood adversity and neural development: Deprivation and threat as distinct dimensions of early experience
A growing body of research has examined the impact of childhood adversity on neural
structure and function. Advances in our understanding of the neurodevelopmental …
structure and function. Advances in our understanding of the neurodevelopmental …
Dimensions of early experience and neural development: deprivation and threat
MA Sheridan, KA McLaughlin - Trends in cognitive sciences, 2014 - cell.com
Over the past decade, a growing area of research has focused on adverse childhood
experiences (ACEs) and their impacts on neural and developmental outcomes. Work in the …
experiences (ACEs) and their impacts on neural and developmental outcomes. Work in the …
Toward understanding how early-life stress reprograms cognitive and emotional brain networks
Y Chen, TZ Baram - Neuropsychopharmacology, 2016 - nature.com
Vulnerability to emotional disorders including depression derives from interactions between
genes and environment, especially during sensitive developmental periods. Adverse early …
genes and environment, especially during sensitive developmental periods. Adverse early …
Early adversity and development: parsing heterogeneity and identifying pathways of risk and resilience
DG Gee - American Journal of Psychiatry, 2021 - Am Psychiatric Assoc
Adversity early in life is common and is a major risk factor for the onset of psychopathology.
Delineating the neurodevelopmental pathways by which early adversity affects mental …
Delineating the neurodevelopmental pathways by which early adversity affects mental …
Early developmental emergence of human amygdala–prefrontal connectivity after maternal deprivation
DG Gee, LJ Gabard-Durnam… - Proceedings of the …, 2013 - National Acad Sciences
Under typical conditions, medial prefrontal cortex (mPFC) connections with the amygdala
are immature during childhood and become adult-like during adolescence. Rodent models …
are immature during childhood and become adult-like during adolescence. Rodent models …
The origins of neuroticism
In this article, we provide a fresh perspective on the developmental origins of neuroticism—a
dimension of temperament marked by elevated stress reactivity resulting in the frequent …
dimension of temperament marked by elevated stress reactivity resulting in the frequent …
The default mode network in healthy individuals: a systematic review and meta-analysis
When the brain is not engaged in goal-directed activities and at rest, there are still
measureable patterns of activity. One resting-state network, the default mode network (DMN) …
measureable patterns of activity. One resting-state network, the default mode network (DMN) …