Polypharmacy: evaluating risks and deprescribing
AD Halli-Tierney, C Scarbrough, D Carroll - American family physician, 2019 - aafp.org
Polypharmacy, defined as regular use of at least five medications, is common in older adults
and younger at-risk populations and increases the risk of adverse medical outcomes. There …
and younger at-risk populations and increases the risk of adverse medical outcomes. There …
Optimizing therapy to prevent avoidable hospital admissions in multimorbid older adults (OPERAM): cluster randomised controlled trial
MR Blum, BTGM Sallevelt, A Spinewine, D O'Mahony… - bmj, 2021 - bmj.com
Objective To examine the effect of optimising drug treatment on drug related hospital
admissions in older adults with multimorbidity and polypharmacy admitted to hospital …
admissions in older adults with multimorbidity and polypharmacy admitted to hospital …
Reducing inappropriate polypharmacy: the process of deprescribing
Inappropriate polypharmacy, especially in older people, imposes a substantial burden of
adverse drug events, ill health, disability, hospitalization, and even death. The single most …
adverse drug events, ill health, disability, hospitalization, and even death. The single most …
A systematic review of the emerging definition of 'deprescribing'with network analysis: implications for future research and clinical practice.
Aims The aim of this study was to identify what definitions have been published for the term
'deprescribing', and determine whether a unifying definition could be reached. A secondary …
'deprescribing', and determine whether a unifying definition could be reached. A secondary …
Deprescribing benzodiazepine receptor agonists: evidence-based clinical practice guideline
Objective To develop an evidence-based guideline to help clinicians make decisions about
when and how to safely taper and stop benzodiazepine receptor agonists (BZRAs); to focus …
when and how to safely taper and stop benzodiazepine receptor agonists (BZRAs); to focus …
The feasibility and effect of deprescribing in older adults on mortality and health: a systematic review and meta‐analysis
Aims Deprescribing is a suggested intervention to reverse the potential iatrogenic harms of
inappropriate polypharmacy. The review aimed to determine whether or not deprescribing is …
inappropriate polypharmacy. The review aimed to determine whether or not deprescribing is …
Prescriber barriers and enablers to minimising potentially inappropriate medications in adults: a systematic review and thematic synthesis
K Anderson, D Stowasser, C Freeman, I Scott - BMJ open, 2014 - bmjopen.bmj.com
Objective To synthesise qualitative studies that explore prescribers' perceived barriers and
enablers to minimising potentially inappropriate medications (PIMs) chronically prescribed …
enablers to minimising potentially inappropriate medications (PIMs) chronically prescribed …
Deprescribing: a narrative review of the evidence and practical recommendations for recognizing opportunities and taking action
Deprescribing can be defined as the process of withdrawal or dose reduction of medications
which are considered inappropriate in an individual. The aim of this narrative review is to …
which are considered inappropriate in an individual. The aim of this narrative review is to …
International Group for Reducing Inappropriate Medication Use & Polypharmacy (IGRIMUP): position statement and 10 recommendations for action
Globally, the number of drug prescriptions is increasing causing more adverse drug events,
which is now a significant cause of mortality, morbidity, and disability that has reached …
which is now a significant cause of mortality, morbidity, and disability that has reached …