Magnesium: biochemistry, nutrition, detection, and social impact of diseases linked to its deficiency

D Fiorentini, C Cappadone, G Farruggia, C Prata - Nutrients, 2021 - mdpi.com
Magnesium plays an important role in many physiological functions. Habitually low intakes
of magnesium and in general the deficiency of this micronutrient induce changes in …

Ischemic heart disease pathophysiology paradigms overview: from plaque activation to microvascular dysfunction

P Severino, A D'Amato, M Pucci, F Infusino… - International journal of …, 2020 - mdpi.com
Ischemic heart disease still represents a large burden on individuals and health care
resources worldwide. By conventions, it is equated with atherosclerotic plaque due to flow …

Magnesium, oxidative stress, inflammation, and cardiovascular disease

M Liu, SC Dudley Jr - Antioxidants, 2020 - mdpi.com
Hypomagnesemia is commonly observed in heart failure, diabetes mellitus, hypertension,
and cardiovascular diseases. Low serum magnesium (Mg) is a predictor for cardiovascular …

Ischemic heart disease and heart failure: role of coronary ion channels

P Severino, A D'Amato, M Pucci, F Infusino… - International journal of …, 2020 - mdpi.com
Heart failure is a complex syndrome responsible for high rates of death and hospitalization.
Ischemic heart disease is one of the most frequent causes of heart failure and it is normally …

Magnesium and pain

HJ Shin, HS Na, SH Do - Nutrients, 2020 - mdpi.com
In terms of antinociceptive action, the main mode of action of magnesium involves its
antagonist action at the N-methyl-d-aspartate (NMDA) receptor, which prevents central …

Eating more sardines instead of fish oil supplementation: Beyond omega-3 polyunsaturated fatty acids, a matrix of nutrients with cardiovascular benefits

HO Santos, TL May, AA Bueno - Frontiers in Nutrition, 2023 - frontiersin.org
Omega-3 polyunsaturated fatty acids (n-3 PUFA) play a significant role in the prevention and
management of cardiometabolic diseases associated with a mild chronic pro-inflammatory …

Advanced heart failure and end-stage heart failure: does a difference exist

P Severino, PJ Mather, M Pucci, A D'Amato… - Diagnostics, 2019 - mdpi.com
Advanced heart failure (AdHF) represents a challenging aspect of heart failure patients.
Because of worsening clinical symptoms, high rates of re-hospitalization and mortality, AdHF …

The significance of low magnesium levels in COVID-19 patients

AE Coman, A Ceasovschih, AD Petroaie, E Popa… - Medicina, 2023 - mdpi.com
Magnesium is the fourth most common mineral in the human body and the second richest
intracellular cation. This element is necessary for many physiological reactions, especially in …

The role of disturbed Mg homeostasis in chronic kidney disease comorbidities

C Rodelo-Haad, MV Pendón-Ruiz de Mier… - Frontiers in cell and …, 2020 - frontiersin.org
Some of the critical mechanisms that mediate chronic kidney disease (CKD) progression are
associated with vascular calcifications, disbalance of mineral metabolism, increased …

Magnesium supplementation attenuates pulmonary hypertension via regulation of magnesium transporters

D Wang, ZL Zhu, DC Lin, SY Zheng, KH Chuang… - …, 2021 - Am Heart Assoc
Pulmonary hypertension (PH) is characterized by profound vascular remodeling and altered
Ca2+ homeostasis in pulmonary arterial smooth muscle cells (PASMCs). Magnesium ion …