[HTML][HTML] Cystic fibrosis microbiology: Advances in antimicrobial therapy
V Waters, A Smyth - Journal of cystic fibrosis, 2015 - Elsevier
Much of the improvement in the survival of individuals with cystic fibrosis (CF) is due to
advancements in antimicrobial treatments. New aerosolized antibiotic formulations have …
advancements in antimicrobial treatments. New aerosolized antibiotic formulations have …
Structure–activity relationships in β‐defensin peptides
K Taylor, PE Barran, JR Dorin - Peptide Science, 2008 - Wiley Online Library
The β‐defensins comprise a large family of small cationic antimicrobial peptides widely
distributed in plants, mammals and insects. These cysteine rich peptides display …
distributed in plants, mammals and insects. These cysteine rich peptides display …
Garlic Revisited: Antimicrobial Activity of Allicin-Containing Garlic Extracts against Burkholderia cepacia Complex
D Wallock-Richards, CJ Doherty, L Doherty… - PLoS …, 2014 - journals.plos.org
The antimicrobial activities of garlic and other plant alliums are primarily based on allicin, a
thiosulphinate present in crushed garlic bulbs. We set out to determine if pure allicin and …
thiosulphinate present in crushed garlic bulbs. We set out to determine if pure allicin and …
Dimerization of antimicrobial peptides: a promising strategy to enhance antimicrobial peptide activity
EN Lorenzon, JP Piccoli… - Protein and peptide …, 2019 - ingentaconnect.com
Antimicrobial resistance is a global health problem with strong social and economic impacts.
The development of new antimicrobial agents is considered an urgent challenge. In this …
The development of new antimicrobial agents is considered an urgent challenge. In this …
Emerging concepts promising new horizons for marine biodiscovery and synthetic biology
FJ Reen, JA Gutiérrez-Barranquero, ADW Dobson… - Marine Drugs, 2015 - mdpi.com
The vast oceans of the world, which comprise a huge variety of unique ecosystems, are
emerging as a rich and relatively untapped source of novel bioactive compounds with …
emerging as a rich and relatively untapped source of novel bioactive compounds with …
Local inflammation induces complement crosstalk which amplifies the antimicrobial response
By eliciting inflammatory responses, the human immunosurveillance system notably
combats invading pathogens, during which acute phase proteins (CRP and cytokines) are …
combats invading pathogens, during which acute phase proteins (CRP and cytokines) are …
Burkholderia cepacia complex: epithelial cell–pathogen confrontations and potential for therapeutic intervention
S McClean, M Callaghan - Journal of medical …, 2009 - microbiologyresearch.org
Burkholderia cepacia complex (Bcc) is an important and virulent pathogen in cystic fibrosis
patients. The interactions between this pathogen and the host lung epithelium are being …
patients. The interactions between this pathogen and the host lung epithelium are being …
Analysis and separation of residues important for the chemoattractant and antimicrobial activities of β-defensin 3
K Taylor, DJ Clarke, B McCullough, W Chin… - Journal of Biological …, 2008 - ASBMB
β-Defensins are important in mammalian immunity displaying both antimicrobial and
chemoattractant activities. Three canonical disulfide intramolecular bonds are believed to be …
chemoattractant activities. Three canonical disulfide intramolecular bonds are believed to be …
Effects of dimerization on the structure and biological activity of antimicrobial peptide Ctx-Ha
EN Lorenzón, GF Cespedes, EF Vicente… - Antimicrobial agents …, 2012 - Am Soc Microbiol
It is well known that cationic antimicrobial peptides (cAMPs) are potential microbicidal
agents for the increasing problem of antimicrobial resistance. However, the physicochemical …
agents for the increasing problem of antimicrobial resistance. However, the physicochemical …
Intracellular survival and innate immune evasion of Burkholderia cepacia: Improved understanding of quorum sensing‐controlled virulence factors, biofilm, and …
PS Ganesh, S Vishnupriya, J Vadivelu… - Microbiology and …, 2020 - Wiley Online Library
Burkholderia cepacia complex (Bcc) are opportunistic pathogens implicated with
nosocomial infections, and high rates of morbidity and mortality, especially in individuals …
nosocomial infections, and high rates of morbidity and mortality, especially in individuals …