Polyphenol‐containing nanoparticles: synthesis, properties, and therapeutic delivery

Y Guo, Q Sun, FG Wu, Y Dai, X Chen - Advanced Materials, 2021 - Wiley Online Library
Polyphenols, the phenolic hydroxyl group‐containing organic molecules, are widely found in
natural plants and have shown beneficial effects on human health. Recently, polyphenol …

Gene therapy: Comprehensive overview and therapeutic applications

N Sayed, P Allawadhi, A Khurana, V Singh, U Navik… - Life sciences, 2022 - Elsevier
Gene therapy is the product of man's quest to eliminate diseases. Gene therapy has three
facets namely, gene silencing using siRNA, shRNA and miRNA, gene replacement where …

Recent advances in polymeric drug delivery systems

YK Sung, SW Kim - Biomaterials Research, 2020 - spj.science.org
Background Polymeric drug delivery systems have been achieved great development in the
last two decades. Polymeric drug delivery has defined as a formulation or a device that …

Cytosolic delivery of nucleic acids: The case of ionizable lipid nanoparticles

M Schlich, R Palomba, G Costabile… - Bioengineering & …, 2021 - Wiley Online Library
Ionizable lipid nanoparticles (LNPs) are the most clinically advanced nano‐delivery system
for therapeutic nucleic acids. The great effort put in the development of ionizable lipids with …

Gene therapy leaves a vicious cycle

R Goswami, G Subramanian, L Silayeva… - Frontiers in …, 2019 - frontiersin.org
The human genetic code encrypted in thousands of genes holds the secret for synthesis of
proteins that drive all biological processes necessary for normal life and death. Though the …

Aptamer functionalized nanomaterials for biomedical applications: Recent advances and new horizons

M Mahmoudpour, S Ding, Z Lyu, G Ebrahimi, D Du… - Nano Today, 2021 - Elsevier
With the advancement of functional nanomaterials and aptamer selection technologies,
aptamer functionalized nanomaterials (AFMs) open various methods to design new sensing …

Inherited retinal diseases: linking genes, disease-causing variants, and relevant therapeutic modalities

N Schneider, Y Sundaresan, P Gopalakrishnan… - Progress in retinal and …, 2022 - Elsevier
Inherited retinal diseases (IRDs) are a clinically complex and heterogenous group of visual
impairment phenotypes caused by pathogenic variants in at least 277 nuclear and …

PLGA-based nanoparticles in cancer treatment

S Rezvantalab, NI Drude, MK Moraveji… - Frontiers in …, 2018 - frontiersin.org
Nanomedicines can be used for a variety of cancer therapies including tumor-targeted drug
delivery, hyperthermia, and photodynamic therapy. Poly (lactic-co-glycolic acid)(PLGA) …

Drug delivery systems for programmed and on-demand release

P Davoodi, LY Lee, Q Xu, V Sunil, Y Sun, S Soh… - Advanced drug delivery …, 2018 - Elsevier
With the advancement in medical science and understanding the importance of
biodistribution and pharmacokinetics of therapeutic agents, modern drug delivery research …

Recent advances in nanomaterials for gene delivery—a review

MK Riley, W Vermerris - Nanomaterials, 2017 - mdpi.com
With the rapid development of nanotechnology in the recent decade, novel DNA and RNA
delivery systems for gene therapy have become available that can be used instead of viral …