Tendinopathy
NL Millar, KG Silbernagel, K Thorborg… - Nature reviews Disease …, 2021 - nature.com
Tendinopathy describes a complex multifaceted pathology of the tendon, characterized by
pain, decline in function and reduced exercise tolerance. The most common overuse …
pain, decline in function and reduced exercise tolerance. The most common overuse …
[HTML][HTML] Tendon injury and repair–A perspective on the basic mechanisms of tendon disease and future clinical therapy
JG Snedeker, J Foolen - Acta biomaterialia, 2017 - Elsevier
Tendon is an intricately organized connective tissue that efficiently transfers muscle force to
the bony skeleton. Its structure, function, and physiology reflect the extreme, repetitive …
the bony skeleton. Its structure, function, and physiology reflect the extreme, repetitive …
Inflammatory mechanisms in tendinopathy–towards translation
NL Millar, GAC Murrell, IB McInnes - Nature reviews rheumatology, 2017 - nature.com
Tendinopathy is a multifactorial spectrum of tendon disorders that affects different
anatomical sites and is characterized by activity-related tendon pain. These disorders are …
anatomical sites and is characterized by activity-related tendon pain. These disorders are …
Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis
E Gracey, A Burssens, I Cambré, G Schett… - Nature reviews …, 2020 - nature.com
Mechanical loading is an important factor in musculoskeletal health and disease. Tendons
and ligaments require physiological levels of mechanical loading to develop and maintain …
and ligaments require physiological levels of mechanical loading to develop and maintain …
Tendon injury: from biology to tendon repair
G Nourissat, F Berenbaum, D Duprez - Nature Reviews Rheumatology, 2015 - nature.com
Tendon is a crucial component of the musculoskeletal system. Tendons connect muscle to
bone and transmit forces to produce motion. Chronic and acute tendon injuries are very …
bone and transmit forces to produce motion. Chronic and acute tendon injuries are very …
Tendon basic science: Development, repair, regeneration, and healing
N Andarawis‐Puri, EL Flatow… - Journal of Orthopaedic …, 2015 - Wiley Online Library
Tendinopathy and tendon rupture are common and disabling musculoskeletal conditions.
Despite the prevalence of these injuries, a limited number of investigators are conducting …
Despite the prevalence of these injuries, a limited number of investigators are conducting …
Therapeutic potential of microRNA in tendon injuries
L Giordano, GD Porta, GM Peretti… - British Medical …, 2020 - academic.oup.com
Introduction The regulatory role of microRNA (miRNA) in several conditions has been
studied, but their function in tendon healing remains elusive. This review summarizes how …
studied, but their function in tendon healing remains elusive. This review summarizes how …
Inflammation activation and resolution in human tendon disease
Improved understanding of the role of inflammation in tendon disease is required to facilitate
therapeutic target discovery. We studied supraspinatus tendons from patients experiencing …
therapeutic target discovery. We studied supraspinatus tendons from patients experiencing …
Advances toward transformative therapies for tendon diseases
BR Freedman, DJ Mooney, E Weber - Science translational medicine, 2022 - science.org
Approved therapies for tendon diseases have not yet changed the clinical practice of
symptomatic pain treatment and physiotherapy. This review article summarizes advances in …
symptomatic pain treatment and physiotherapy. This review article summarizes advances in …
Tendon development and musculoskeletal assembly: emerging roles for the extracellular matrix
A Subramanian, TF Schilling - Development, 2015 - journals.biologists.com
Tendons and ligaments are extracellular matrix (ECM)-rich structures that interconnect
muscles and bones. Recent work has shown how tendon fibroblasts (tenocytes) interact with …
muscles and bones. Recent work has shown how tendon fibroblasts (tenocytes) interact with …