[HTML][HTML] Recent advances on quinazoline derivatives: A potential bioactive scaffold in medicinal chemistry
This paper intended to explore and discover recent therapeutic agents in the area of
medicinal chemistry for the treatment of various diseases. Heterocyclic compounds …
medicinal chemistry for the treatment of various diseases. Heterocyclic compounds …
Epidermal growth factor receptor inhibitors as potential anticancer agents: An update of recent progress
Epidermal growth factor receptor (EGFR) is a vital intermediate in cell signaling pathway
including cell proliferation, angiogenesis, apoptosis, and metastatic spread and also having …
including cell proliferation, angiogenesis, apoptosis, and metastatic spread and also having …
Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity
HSA ElZahabi, MS Nafie, D Osman… - European Journal of …, 2021 - Elsevier
This work presents the design and synthesis of a series of new quinazolin-4-one derivatives,
based on the established effectiveness of quinazoline-based small molecules as anticancer …
based on the established effectiveness of quinazoline-based small molecules as anticancer …
Cell cycle arrest and apoptosis-inducing ability of benzimidazole derivatives: design, synthesis, docking, and biological evaluation
S Nazreen, ASA Almalki, SEI Elbehairi, AA Shati… - Molecules, 2022 - mdpi.com
In the current study, new benzimidazole-based 1, 3, 4-oxadiazole derivatives have been
synthesized and characterized by NMR, IR, MS, and elemental analysis. The final …
synthesized and characterized by NMR, IR, MS, and elemental analysis. The final …
An appraisal of anticancer activity with structure–activity relationship of quinazoline and quinazolinone analogues through EGFR and VEGFR inhibition: A review
Cancer is one of the leading causes of death. Globally a huge number of deaths and new
incidences are reported annually. Heterocyclic compounds have been proved to be very …
incidences are reported annually. Heterocyclic compounds have been proved to be very …
Suppression Effect of Ulva lactuca Selenium Nanoparticles (USeNPs) on HepG2 Carcinoma Cells Resulting from Degradation of Epidermal Growth Factor Receptor …
MEM Makhlof, FM Albalwe, TM Al-Shaikh… - Applied Sciences, 2022 - mdpi.com
The current study sought to assess the antitumor, anticancer, and antioxidant efficacy of Ulva
lactuca-mediated selenium nanoparticles by using an in vitro model of human …
lactuca-mediated selenium nanoparticles by using an in vitro model of human …
Discovery of a novel series of substituted quinolines acting as anticancer agents and selective EGFR blocker: Molecular docking study
Abstract A Ta 2 O 5-anchored-piperidine-4-carboxylic acid (PPCA) nanoparticle has been
synthesized and characterized. It was then used as a highly effective nanocatalyst for the …
synthesized and characterized. It was then used as a highly effective nanocatalyst for the …
Development of penipanoid C-inspired 2-benzoyl-1-methyl-2, 3-dihydroquinazolin-4 (1H)-one derivatives as potential EGFR inhibitors: Synthesis, anticancer …
A novel class of penipanoid C-inspired 2-benzoyl-1-methyl-2, 3-dihydroquinazolin-4 (1H)-
ones (3a-3f) and 1-methyl-2-(3, 4, 5-trihydroxybenzoyl)-2, 3-dihydroquinazolin-4 (1H)-one …
ones (3a-3f) and 1-methyl-2-(3, 4, 5-trihydroxybenzoyl)-2, 3-dihydroquinazolin-4 (1H)-one …
[HTML][HTML] Enzymatic synthesis of fluorinated compounds
X Cheng, L Ma - Applied Microbiology and Biotechnology, 2021 - Springer
Fluorinated compounds are widely used in the fields of molecular imaging, pharmaceuticals,
and materials. Fluorinated natural products in nature are rare, and the introduction of …
and materials. Fluorinated natural products in nature are rare, and the introduction of …
Discovery of Simple Diacylhydrazine-Functionalized Cinnamic Acid Derivatives as Potential Microtubule Stabilizers
X Zhou, YH Fu, YY Zou, J Meng, GP Ou-Yang… - International Journal of …, 2022 - mdpi.com
To develop novel microtubule-binding agents for cancer therapy, an array of N-cinnamoyl-N'-
(substituted) acryloyl hydrazide derivatives were facilely synthesized through a two-step …
(substituted) acryloyl hydrazide derivatives were facilely synthesized through a two-step …