Rho GTPases are a family of small G proteins that regulate a wide array of cellular
processes related to their key roles controlling the cytoskeleton. Cancer is a multistep …

Kinesins are a family of molecular motors that travel unidirectionally along microtubule
tracks to fulfil their many roles in intracellular transport or cell division. Over the past few …

There is a long-held consensus that several proteins are unique to small extracellular
vesicles (EVs), such as exosomes. However, recent studies have shown that several of …

Cytokinesis mediates the physical separation of dividing cells after chromosome
segregation. In animal cell cytokinesis, a contractile ring, mainly composed of actin and …

Cells are active materials; they can change shape using internal energy to build contractile
networks of actin filaments and myosin motors. Contractility of the actomyosin cortex is tightly …

Cytokinesis is the process by which cells physically separate after the duplication and
spatial segregation of the genetic material. A number of general principles apply to this …

Cell division ends with the physical separation of the two daughter cells, a process known as
cytokinesis. This final event ensures that nuclear and cytoplasmic contents are accurately …

Rho GTPases are involved in the acquisition of all the hallmarks of cancer, which comprise 6
biological capabilities acquired during the development of human tumors. The hallmarks …

Retinoblastoma is a paediatric ocular tumour that continues to reveal much about the
genetic basis of cancer development. Study of genomic aberrations in retinoblastoma …

Proper chromosome segregation into two future daughter cells requires the mitotic spindle to
elongate in anaphase. However, although some candidate proteins are implicated in this …