Vaccines and therapeutics for immunocompromised patients with COVID-19

S Shoham, C Batista, YB Amor, O Ergonul… - …, 2023 - thelancet.com
The COVID-19 pandemic has disproportionately impacted immunocompromised patients.
This diverse group is at increased risk for impaired vaccine responses, progression to …

[HTML][HTML] Clinical outcome in solid organ transplant recipients affected by COVID-19 compared to general population: a systematic review and meta-analysis

M Gatti, M Rinaldi, L Bussini, C Bonazzetti… - Clinical Microbiology …, 2022 - Elsevier
Background A significant increased risk of complications and mortality in
immunocompromised patients affected by COVID-19 has been described. However, the …

Early clinical experience with nirmatrelvir/ritonavir for the treatment of COVID‐19 in solid organ transplant recipients

DM Salerno, DL Jennings, NW Lange… - American Journal of …, 2022 - Wiley Online Library
Nirmatrelvir/ritonavir (NR) use has not yet been described in solid organ transplant
recipients (SOTRs) with mild COVID‐19. The objective was to evaluate outcomes among …

The association between severe or death COVID-19 and solid organ transplantation: a systematic review and meta-analysis

G Ao, Y Wang, X Qi, B Nasr, M Bao, M Gao, Y Sun… - Transplantation …, 2021 - Elsevier
Background The effect of solid organ transplantation (SOT) on the severity and mortality of
coronavirus disease 2019 (COVID-19) remained controversial. There is still no consensus …

COVID-19 and solid organ transplantation: Finding the right balance

R Opsomer, D Kuypers - Transplantation Reviews, 2022 - Elsevier
Background The COVID-19 pandemic has a great impact on solid organ transplant (SOT)
recipients due to their comorbidities and their maintenance immunosuppression. So far …

The immunology of SARS-CoV-2 infection and vaccines in solid organ transplant recipients

D Dęborska-Materkowska, D Kamińska - Viruses, 2021 - mdpi.com
Since its outbreak in December 2019, the coronavirus disease 2019 (COVID-19) pandemic,
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), led to an …

[HTML][HTML] Coronavirus disease–2019 and the intestinal tract: An overview

GGF Alberca, RL Solis-Castro… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection can progress to a
severe respiratory and systemic disease named coronavirus disease–2019 (COVID-19) …

[HTML][HTML] Orexins: A promising target to digestive cancers, inflammation, obesity and metabolism dysfunctions

A Couvineau, T Voisin, P Nicole, V Gratio… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Hypothalamic neuropeptides named hypocretin/orexins which were identified in 1998
regulate critical functions such as wakefulness in the central nervous system. These past 20 …

Executive summary of the consensus statement of the group for the study of infection in transplantation and other immunocompromised host (GESITRA-IC) of the …

S Herrera, JM Aguado, FJ Candel, E Cordero… - Transplantation …, 2023 - Elsevier
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) arose in December 2019
in China rapidly evolving to the Coronavirus Disease 2019 (COVID-19) pandemic. Since …

Impact of solid organ transplant status on outcomes of hospitalized patients with COVID‐19 infection

J Schaenman, H Byford, T Grogan… - Transplant Infectious …, 2022 - Wiley Online Library
Background The COVID‐19 pandemic has caused significant morbidity and mortality in solid
organ transplant (SOT) recipients. However, it remains unclear whether the risk factor for …