Glutathione-depleting nanomedicines for synergistic cancer therapy
X Cheng, HD Xu, HH Ran, G Liang, FG Wu - ACS nano, 2021 - ACS Publications
Cancer cells frequently exhibit resistance to various molecular and nanoscale drugs, which
inevitably affects the drugs' therapeutic outcomes. Overexpression of glutathione (GSH) has …
inevitably affects the drugs' therapeutic outcomes. Overexpression of glutathione (GSH) has …
Photosensitization and controlled photosensitization with BODIPY dyes
Highly versatile BODIPY dyes proved themselves to be very useful as photosensitizers.
These dyes can be derivatized to absorb essentially anywhere in the visible the near IR …
These dyes can be derivatized to absorb essentially anywhere in the visible the near IR …
Application of multifunctional BODIPY in photodynamic therapy
At present, BODIPY and its derivatives are a kind of multifunctional photosensitive organic
dyes, because of their small Stokes shift, strong absorption, narrow absorption and …
dyes, because of their small Stokes shift, strong absorption, narrow absorption and …
Redox status expressed as GSH: GSSG ratio as a marker for oxidative stress in paediatric tumour patients
O Zitka, S Skalickova, J Gumulec… - Oncology …, 2012 - spandidos-publications.com
Oxidative stress causes profound alterations of various biological structures, including
cellular membranes, lipids, proteins and nucleic acids, and it is involved in numerous …
cellular membranes, lipids, proteins and nucleic acids, and it is involved in numerous …
Endocrine resistance in hormone receptor positive breast cancer–from mechanism to therapy
A Rani, J Stebbing, G Giamas, J Murphy - Frontiers in endocrinology, 2019 - frontiersin.org
The importance and role of the estrogen receptor (ER) pathway has been well-documented
in both breast cancer (BC) development and progression. The treatment of choice in women …
in both breast cancer (BC) development and progression. The treatment of choice in women …
Glutathione levels in human tumors
MP Gamcsik, MS Kasibhatla, SD Teeter, OM Colvin - Biomarkers, 2012 - Taylor & Francis
This review summarizes clinical studies in which glutathione was measured in tumor tissue
from patients with brain, breast, gastrointestinal, gynecological, head and neck and lung …
from patients with brain, breast, gastrointestinal, gynecological, head and neck and lung …
Heparin-functionalized polymeric biomaterials in tissue engineering and drug delivery applications
Heparin plays an important role in many biological processes via its interaction with various
proteins, and hydrogels and nanoparticles comprising heparin exhibit attractive properties …
proteins, and hydrogels and nanoparticles comprising heparin exhibit attractive properties …
Antioxidant activity of sulfur and selenium: a review of reactive oxygen species scavenging, glutathione peroxidase, and metal-binding antioxidant mechanisms
EE Battin, JL Brumaghim - Cell biochemistry and biophysics, 2009 - Springer
It is well known that oxidation caused by reactive oxygen species (ROS) is a major cause of
cellular damage and death and has been implicated in cancer, neurodegenerative, and …
cellular damage and death and has been implicated in cancer, neurodegenerative, and …
Ultra-fast colorimetric detection of glutathione by magnetic Fe NPs with peroxidase-like activity
L Zhang, J Wang, C Zhao, F Zhou, C Yao… - Sensors and Actuators B …, 2022 - Elsevier
The nanozymes-based sensing platforms have been attracted in recent years due to their
outstanding performances in the practical applications. In this work, the magnetic Fe …
outstanding performances in the practical applications. In this work, the magnetic Fe …
Oxidative stress indexes for diagnosis of health or disease in humans
MA Sánchez-Rodríguez… - Oxidative medicine and …, 2019 - Wiley Online Library
Oxidative stress (OS) is the imbalance between oxidant and antioxidant molecules, in favor
of oxidants, that causes aging and disease. Many studies have been published that …
of oxidants, that causes aging and disease. Many studies have been published that …