Inhalable nanoparticle-based dry powder formulations for respiratory diseases: challenges and strategies for translational research
The emergence of novel respiratory infections (eg, COVID-19) and expeditious development
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …
Advances in the application of nanomaterials as treatments for bacterial infectious diseases
Bacteria-targeting nanomaterials have been widely used in the diagnosis and treatment of
bacterial infectious diseases. These nanomaterials show great potential as antimicrobial …
bacterial infectious diseases. These nanomaterials show great potential as antimicrobial …
Spray freeze dried niclosamide nanocrystals embedded dry powder for high dose pulmonary delivery
S Zhang, S Yan, K Lu, S Qiu, XD Chen, WD Wu - Powder Technology, 2023 - Elsevier
Based on the drug repositioning strategy, niclosamide (NCL) has shown potential
applications for treating COVID-19. However, the development of new formulations for …
applications for treating COVID-19. However, the development of new formulations for …
Inhalable Polymeric Microparticles for Phage and Photothermal Synergistic Therapy of Methicillin-Resistant Staphylococcus aureus Pneumonia
MY Liu, X Liu, CY Wang, QQ Wan, YF Tian, SL Liu… - Nano Letters, 2024 - ACS Publications
Acute methicillin-resistant Staphylococcus aureus (MRSA) pneumonia is a common and
serious lung infection with high morbidity and mortality rates. Due to the increasing antibiotic …
serious lung infection with high morbidity and mortality rates. Due to the increasing antibiotic …
[HTML][HTML] Drug combination of ciprofloxacin and polymyxin b for the treatment of multidrug–resistant acinetobacter baumannii infections: a drug pair limiting the …
Polymyxins are considered as last–resort antibiotics to treat infections caused by
Acinetobacter baumannii. However, there are increasing reports of resistance in A …
Acinetobacter baumannii. However, there are increasing reports of resistance in A …
Promising brain biodistribution of insulin via intranasal dry powder for nose-to-brain delivery
Nose-to-brain delivery (NTBD) offering potential benefits for treating Alzheimer's disease. In
previous research, insulin dry powder (IDP) formulation for NTBD was developed, exhibiting …
previous research, insulin dry powder (IDP) formulation for NTBD was developed, exhibiting …
[HTML][HTML] Electrospinning as a method for preparation of redispersible dry product with high content of magnetic nanoparticles
One of the key technological challenges in the development of iron-oxide-based magnetic
nanoparticles (MNPs) is their long-term physical stability in colloidal dispersions. This can …
nanoparticles (MNPs) is their long-term physical stability in colloidal dispersions. This can …
Spray dried inhalable ivacaftor co-amorphous microparticle formulations with leucine achieved enhanced in vitro dissolution and superior aerosol performance
J Guan, H Yuan, S Yu, S Mao, QT Zhou - International journal of …, 2022 - Elsevier
The present study aimed to develop inhalable powder formulations with both dissolution
enhancement and superior aerodynamic properties for potential pulmonary delivery of a …
enhancement and superior aerodynamic properties for potential pulmonary delivery of a …
Inhaled Colistimethate Sodium in the Management of Patients with Bronchiectasis Infected by Pseudomonas aeruginosa: A Narrative Review of Current Evidence
D De la Rosa-Carrillo, G Suárez-Cuartín… - Infection and Drug …, 2022 - Taylor & Francis
International guidelines on the treatment of bronchiectasis indicate that the use of inhaled
antibiotics is effective, especially in symptomatic chronic bronchial infection (CBI) due to …
antibiotics is effective, especially in symptomatic chronic bronchial infection (CBI) due to …
New Antimicrobial Strategies to Treat Multi-Drug Resistant Infections Caused by Gram-Negatives in Cystic Fibrosis
People with cystic fibrosis (CF) suffer from recurrent bacterial infections which induce
inflammation, lung tissue damage and failure of the respiratory system. Prolonged exposure …
inflammation, lung tissue damage and failure of the respiratory system. Prolonged exposure …