Histotripsy is the first noninvasive, non-ionizing, and non-thermal ablation technology
guided by real-time imaging. Using focused ultrasound delivered from outside the body …

High intensity focused ultrasound (HIFU) is a non-invasive and non-ionizing sonic energy-
based therapeutic technology for inducing thermal and non-thermal effects in tissues …

Rationale Current hepatic locoregional therapies are limited in terms of effectiveness and
toxicities. Given promising pre-clinical results, a first in-human trial was designed to assess …

Since its inception about two decades ago, histotripsy–a non-thermal mechanical tissue
ablation technique–has evolved into a spectrum of methods, each with distinct potentiating …

Pancreatic cancer is a significant cause of cancer-related deaths in the United States with an
abysmal five-year overall survival rate that is under 9%. Reasons for this mortality include …

Purpose Image-guided thermal ablation are established treatment options for non-surgical
patients with primary and metastatic liver cancers. However, there are limitations with …

The study described here examined the effects of cavitation nuclei characteristics on
histotripsy. High-speed optical imaging was used to compare bubble cloud behavior and …

Osteosarcoma (OS) is a primary bone tumor affecting both dogs and humans. Histotripsy is a
non-thermal, non-invasive focused ultrasound method using controlled acoustic cavitation to …

Objective. Histotripsy is a non-thermal focused ultrasound ablation method that destroys
tissue through the generation of a cavitation bubble cloud. Previous work studying intrinsic …

Simple Summary Histotripsy is a novel technique that mechanically disrupts tumors, through
precisely controlled acoustic cavitation. There is insufficient evidence regarding the effects of …