Inclusion body myositis: clinical features and pathogenesis

SA Greenberg - Nature Reviews Rheumatology, 2019 - nature.com
Inclusion body myositis (IBM) is often viewed as an enigmatic disease with uncertain
pathogenic mechanisms and confusion around diagnosis, classification and prospects for …

LGL leukemia: from pathogenesis to treatment

T Lamy, A Moignet… - Blood, The Journal of the …, 2017 - ashpublications.org
Large granular lymphocyte (LGL) leukemia has been recognized by the World Health
Organization classifications amongst mature T-cell and natural killer (NK) cell neoplasms …

STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia

A Jerez, MJ Clemente, H Makishima… - Blood, The Journal …, 2012 - ashpublications.org
Chronic lymphoproliferative disorders of natural killer cells (CLPD-NKs) and T-cell large
granular lymphocytic leukemias (T-LGLs) are clonal lymphoproliferations arising from either …

Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8+ T-cell large granular lymphocytic leukemia

J Huuhtanen, D Bhattacharya, T Lönnberg… - Nature …, 2022 - nature.com
T cell large granular lymphocytic leukemia (T-LGLL) is a rare lymphoproliferative disorder of
mature, clonally expanded T cells, where somatic-activating STAT3 mutations are common …

Highly differentiated cytotoxic T cells in inclusion body myositis

SA Greenberg, JL Pinkus, SW Kong, C Baecher-Allan… - Brain, 2019 - academic.oup.com
Inclusion body myositis is a late onset treatment-refractory autoimmune disease of skeletal
muscle associated with a blood autoantibody (anti-cN1A), an HLA autoimmune haplotype …

How I treat LGL leukemia

T Lamy, TP Loughran Jr - Blood, The Journal of the American …, 2011 - ashpublications.org
Large granular lymphocyte (LGL) leukemia is characterized by a clonal expansion of either
CD3+ cytotoxic T or CD3− NK cells. Prominent clinical features of T-LGL leukemia include …

Congenital neutropenia: diagnosis, molecular bases and patient management

J Donadieu, O Fenneteau, B Beaupain… - Orphanet journal of rare …, 2011 - Springer
The term congenital neutropenia encompasses a family of neutropenic disorders, both
permanent and intermittent, severe (< 0.5 G/l) or mild (between 0.5-1.5 G/l), which may also …

Latest advances in the diagnosis and treatment of large granular lymphocytic leukemia

A Moignet, T Lamy - … Society of Clinical Oncology Educational Book, 2018 - ascopubs.org
Large granular lymphocyte (LGL) leukemia has been recognized in the World Health
Organization classifications among mature T cell and natural killer cell neoplasms and is …

Natural killer cells in human autoimmune diseases

N Schleinitz, F Vély, JR Harlé, E Vivier - Immunology, 2010 - Wiley Online Library
Natural killer (NK) cells have been implicated in tumour surveillance and in the early control
of several microbial infections. In autoimmune disease their involvement in these processes …

Association of inclusion body myositis with T cell large granular lymphocytic leukaemia

SA Greenberg, JL Pinkus, AA Amato, T Kristensen… - Brain, 2016 - academic.oup.com
Abstract See Hohlfeld and Schulze-Koops (doi: 10.1093/brain/aww053) for a scientific
commentary on this article. Inclusion body myositis and T cell large granular lymphocytic …