It is estimated that fungal infections, caused most commonly by Candida albicans,
Aspergillus fumigatus and Cryptococcus neoformans, result in more deaths annually than …

More than 1.5 million fungal species are estimated to live in vastly different environmental
niches. Despite each unique host environment, fungal cells sense certain fundamentally …

Cryptococcus neoformans is the causative agent of cryptococcosis, a disease with poor
patient outcomes that accounts for approximately 180,000 deaths each year. Patient …

Human and plant pathogenic fungi have a major impact on public health and agriculture.
Although these fungi infect very diverse hosts and are often highly adapted to specific host …

Fungal pathogens destroy our crops and cause hazardous human infections, therefore
threatening our health and food security. The ability of fungal pathogens to sense and …

Fungal opportunistic pathogens colonize various environments, from plants and wood to
human and animal tissue. Regarding human pathogens, one great challenge during …

The incidence of human fungal infections is increasing due to the expansion of the
immunocompromised patient population. The continuous use of different antifungal agents …

To respond to the changing environment, cells must be able to sense external conditions.
This is important for many processes including growth, mating, the expression of virulence …

Plant pathogens are parasites that live at the expense of their host. While fungal pathogens
are the largest group of plant pathogens, other important plant pathogens include bacteria …

Cryptococcus neoformans and its sister species Cryptococcus deuterogattii are important
human fungal pathogens. Despite their phylogenetically close relationship, these two …