Strategies of neutrophil diversification
M Palomino-Segura, J Sicilia, I Ballesteros… - Nature …, 2023 - nature.com
Neutrophils are formidable defenders. Their vast numbers, constant production, high
cytotoxicity and capacity to produce extracellular traps, underlie their ability to efficiently …
cytotoxicity and capacity to produce extracellular traps, underlie their ability to efficiently …
Clonal hematopoiesis and its impact on the aging osteo-hematopoietic niche
S Winter, KS Götze, JS Hecker, KH Metzeler… - Leukemia, 2024 - nature.com
Clonal hematopoiesis (CH) defines a premalignant state predominantly found in older
persons that increases the risk of developing hematologic malignancies and age-related …
persons that increases the risk of developing hematologic malignancies and age-related …
Measurable (Minimal) Residual Disease in Myelodysplastic Neoplasms (MDS): Current State and Perspectives
Simple Summary Myelodysplastic Neoplasms (MDS) are a type of blood cancer presenting
as ineffective production of blood cells, even though the bone marrow appears active …
as ineffective production of blood cells, even though the bone marrow appears active …
Hematopoietic Clonal Evolution Goes Spatial
R Austin, I Aifantis - Blood Cancer Discovery, 2024 - AACR
The spatial distribution of cells carrying clonal hematopoiesis mutations in the bone marrow
and the potential role of interactions with the microenvironment are largely unknown. This …
and the potential role of interactions with the microenvironment are largely unknown. This …
Approaches for the diagnosis and treatment of VEXAS syndrome: the importance of clinical suspicion and the use of methotrexate
Abstract Vacuoles, E1-enzyme, X-linked, Autoinflammatory, Somatic (VEXAS) syndrome is
caused by mutations in the UBA1 gene in myeloid precursors, leading to systemic …
caused by mutations in the UBA1 gene in myeloid precursors, leading to systemic …
Spatial mapping of hematopoietic clones in human bone marrow
AL Young, HC Davis, MJ Cox, TM Parsons… - Blood cancer …, 2024 - AACR
Clonal hematopoiesis (CH) is the expansion of somatically mutated cells in the
hematopoietic compartment of individuals without hematopoietic dysfunction. Large CH …
hematopoietic compartment of individuals without hematopoietic dysfunction. Large CH …
Implementation of advanced analytical methods MeD-seq and LC-MS/MS for assessing the epigenetic profile of high-risk myelodysplastic syndrome
T Nikolopoulos, E Bochalis, T Chatzilygeroudi… - 2024 - researchsquare.com
Abstract Treatment decision and response assessment in myelodysplastic syndromes
(MDS) can be enhanced by the implementation of advanced diagnostic and prognostic …
(MDS) can be enhanced by the implementation of advanced diagnostic and prognostic …