Piperazine, is privileged six membered nitrogen containing heterocyclic ring also known as
1, 4-Diazacyclohexane. Consequently, piperazine is a versatile medicinally important …

Tuberculosis (TB) has been considered as the highly chronic, contagious and infectious
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …

Tuberculosis is the infectious disease caused by mycobacterium tuberculosis (Mtb),
responsible for the utmost number of deaths annually across the world. Herein, twenty-one …

Tuberculosis (TB), one of the deadliest diseases is shattering the health and socioeconomic
status of the society. The emergence of multidrug resistant (MDR) and extremely drug …

Nitro-containing compounds have emerged as important agents in the control of
tuberculosis (TB). From a whole-cell high-throughput screen for Mycobacterium tuberculosis …

Ever increasing drug resistance has become an impeding threat that continues to hamper
effective tackling of otherwise treatable tuberculosis (TB). Such dismal situation necessitates …

In this study, a series of sulfonamide compounds was designed and synthesized through the
systematic optimization of the antibacterial agent sulfaphenazole for the treatment of …

Pulmonary tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis
(MTB) and still remains one of the foremost fatal infectious diseases, infecting nearly a third …

Three series of novel nitrofuran-1, 3, 4-oxadiazole hybrids were designed and synthesized
as new anti-TB agents. The structure activity relationship study indicated that the linkers and …

A series of novel nitrofuranyl methyl N-heterocycles based on the structure of IIIM-MCD-211
were designed and synthesized. Compounds 6d, 8b and 12a show excellent activity against …