[HTML][HTML] Desaturases and elongases involved in long-chain polyunsaturated fatty acid biosynthesis in aquatic animals: From genes to functions

Ó Monroig, AC Shu-Chien, N Kabeya, DR Tocher… - Progress in lipid …, 2022 - Elsevier
Marine ecosystems are rich in “omega-3” long-chain (C 20-24) polyunsaturated fatty acids
(LC-PUFA). Their production has been historically accepted to derive mostly from marine …

Long-chain polyunsaturated fatty acid biosynthesis in chordates: Insights into the evolution of Fads and Elovl gene repertoire

LFC Castro, DR Tocher, O Monroig - Progress in lipid research, 2016 - Elsevier
Long-chain polyunsaturated fatty acids (LC-PUFA) are major components of complex lipid
molecules and are also involved in numerous critical biological processes. Studies …

Regulation of long-chain polyunsaturated fatty acid biosynthesis in teleost fish

D Xie, C Chen, Y Dong, C You, S Wang… - Progress in Lipid …, 2021 - Elsevier
Abstract Omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA, C 20-24),
including eicosapentaenoic acid (EPA, 20: 5n-3) and docosahexaenoic acid (DHA, 22: 6n …

[HTML][HTML] Desaturases and elongases involved in polyunsaturated fatty acid biosynthesis in aquatic invertebrates: a comprehensive review

Ó Monroig, N Kabeya - Fisheries Science, 2018 - Springer
Invertebrates represent a large proportion of the biomass in aquatic ecosystems, particularly
in the ocean. In recent years, invertebrates have been well-consolidated models in …

[HTML][HTML] Polyunsaturated fatty acids in fish tissues more closely resemble algal than terrestrial diet sources

N Ebm, F Guo, MT Brett, SE Bunn, MJ Kainz - Hydrobiologia, 2021 - Springer
Abstract The River Continuum Concept implies that consumers in headwater streams have
greater dietary access to terrestrial basal resources, but recent studies have highlighted the …

[HTML][HTML] Functional Desaturase Fads1 (Δ5) and Fads2 (Δ6) Orthologues Evolved before the Origin of Jawed Vertebrates

LFC Castro, O Monroig, MJ Leaver, J Wilson, I Cunha… - PloS one, 2012 - journals.plos.org
Long-chain polyunsaturated fatty acids (LC-PUFAs) such as arachidonic (ARA),
eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids are essential components of …

Sustainable alternatives to dietary fish oil in tropical fish aquaculture

R Alhazzaa, PD Nichols, CG Carter - Reviews in Aquaculture, 2019 - Wiley Online Library
Marine tropical carnivorous (MTC) fish are less tolerant to high dietary lipid compared with
cold and temperate climate fish. However, insufficient n‐3 long‐chain (≥ C20) …

Delta-8 desaturation activity varies among fatty acyl desaturases of teleost fish: high activity in delta-6 desaturases of marine species

Ó Monroig, Y Li, DR Tocher - … and Physiology Part B: Biochemistry and …, 2011 - Elsevier
The benefits of dietary fish and fish oil are derived from n-3 long-chain polyunsaturated fatty
acids (LC-PUFA) that have beneficial effects in a range of human diseases and pathologies …

[HTML][HTML] Regulation of FADS2 transcription by SREBP-1 and PPAR-α influences LC-PUFA biosynthesis in fish

X Dong, P Tan, Z Cai, H Xu, J Li, W Ren, H Xu, R Zuo… - Scientific reports, 2017 - nature.com
The present study was conducted to explore the mechanisms leading to differences among
fishes in the ability to biosynthesize long-chain polyunsaturated fatty acids (LC-PUFAs) …

Elongation of long-chain fatty acids in rabbitfish Siganus canaliculatus: Cloning, functional characterisation and tissue distribution of Elovl5-and Elovl4-like elongases

O Monroig, S Wang, L Zhang, C You, DR Tocher, Y Li - Aquaculture, 2012 - Elsevier
Elongases of very long-chain fatty acids (Elovl) catalyse the rate-limiting step of the
elongation pathway that results in net 2C elongation of pre-existing fatty acyl chains. As the …