Based on experimental concentration depth profiles of the antiinflammatory drug
dexamethasone in human skin, we model the time-dependent drug penetration by the 1D …

Introduction: Mathematical models of dermal transport offer the advantages of being much
faster and less expensive than in vitro or in vivo studies. The number of methods used to …

Objective Tape stripping is an often‐used non‐invasive destructive method to investigate the
skin penetration of a substance. In recent years, however, the suitability of confocal Raman …

Transdermal drug delivery is a key technology for administering drugs. However, most
devices are “one-size-fits-all”, even though drug diffusion through the skin varies …

Transdermal drug delivery systems are a key technology to administer drugs with a high first-
pass effect in a non-invasive and controlled way. Physics-based modeling and simulation …

Based on experimental drug concentration profiles in healthy as well as tape-stripped ex
vivo human skin, we model the penetration of the antiinflammatory drug dexamethasone into …

For some time, in-silico models to address substance transport into and through the skin are
gaining more and more importance in different fields of science and industry. In particular …

Frequently, analysis of skin absorption does not only require the careful evaluation of
experimental data but also the fundamental understanding of underlying physics to apply …

Tape stripping is a standard technique for investigating drug penetration into skin. The
minimally invasive nature and easy procedure enable in vitro and in vivo studies and …

In biologischen Systemen führt die Wechselwirkung eines Partikels mit seiner Umgebung zu
diffusivem Verhalten. Diese Art der Bewegung kann auf verschiedenen Längen-und …