Anticancer activity of curcumin and its analogues: preclinical and clinical studies

A Allegra, V Innao, S Russo, D Gerace… - Cancer …, 2017 - Taylor & Francis
Curcumin has been shown to have a wide variety of therapeutic effects, ranging from anti-
inflammatory, chemopreventive, anti-proliferative, and anti-metastatic. This review provides …

An overview on immunoregulatory and anti-inflammatory properties of chrysin and flavonoids substances

M Zeinali, SA Rezaee, H Hosseinzadeh - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Inflammation and the pro-inflammatory cytokines are associated with numerous chronic
diseases. Studies suggest that flavonoids, plant polyphenolic compound derivatives from …

Curcumin: a modulator of inflammatory signaling pathways in the immune system

KR Kahkhaie, A Mirhosseini, A Aliabadi… - …, 2019 - Springer
Curcumin is a natural compound derived from the spice, turmeric, that has been extensively
reported for its efficacy in controlling or treatment of several inflammatory diseases. There is …

[HTML][HTML] Curcumin modulates macrophage polarization through the inhibition of the toll-like receptor 4 expression and its signaling pathways

Y Zhou, T Zhang, X Wang, X Wei, Y Chen… - Cellular Physiology and …, 2015 - karger.com
Background: Curcumin, the active ingredient in curcuma rhizomes, has a wide range of
therapeutic effects. However, its atheroprotective activity in human acute monocytic …

Curcumin as a potential modulator of M1 and M2 macrophages: new insights in atherosclerosis therapy

AA Momtazi-Borojeni, E Abdollahi, B Nikfar… - Heart failure …, 2019 - Springer
Accumulation of macrophages within the artery wall is an eminent feature of atherosclerotic
plaques. Macrophages are influenced by various plaque microenvironmental stimuli, such …

Effects of curcumin on microglial cells

F Ghasemi, H Bagheri, GE Barreto, MI Read… - Neurotoxicity …, 2019 - Springer
Microglia are innate immune system cells which reside in the central nervous system (CNS).
Resting microglia regulate the homeostasis of the CNS via phagocytic activity to clear …

Inhalation treatment of idiopathic pulmonary fibrosis with curcumin large porous microparticles

Y Hu, M Li, M Zhang, Y Jin - International journal of pharmaceutics, 2018 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with high
mortality and poor prognosis. Curcumin shows anti-inflammatory effect by suppressing pro …

The role of phytochemicals in sepsis: A mechanistic and therapeutic perspective

B Alikiaii, M Bagherniya, G Askari, TP Johnston… - …, 2021 - Wiley Online Library
Sepsis and septic shock are still a leading cause of mortality and morbidity in intensive care
units worldwide. Sepsis is an uncontrolled and excessive response of the innate immune …

Medicinal plants and bioactive natural products as inhibitors of NLRP3 inflammasome

M Bagherniya, H Khedmatgozar… - Phytotherapy …, 2021 - Wiley Online Library
The NLR family, pyrin domain‐containing 3 (NLRP3) inflammasome is a multiprotein
complex that induces caspase‐1 activation and the downstream substrates involved with the …

Attenuation of the macrophage inflammatory activity by TiO2 nanotubes via inhibition of MAPK and NF-κB pathways

P Neacsu, A Mazare, P Schmuki… - International journal of …, 2015 - Taylor & Francis
Biomaterial implantation in a living tissue triggers the activation of macrophages in
inflammatory events, promoting the transcription of pro-inflammatory mediator genes. The …