Biomedical optical fibers

MR Sarabi, N Jiang, E Ozturk, AK Yetisen, S Tasoglu - Lab on a Chip, 2021 - pubs.rsc.org
Optical fibers with the ability to propagate and transfer data via optical signals have been
used for decades in medicine. Biomaterials featuring the properties of softness …

Deep-brain optical recording of neural dynamics during behavior

ZC Zhou, A Gordon-Fennell, SC Piantadosi, N Ji… - Neuron, 2023 - cell.com
In vivo fluorescence recording techniques have produced landmark discoveries in
neuroscience, providing insight into how single cell and circuit-level computations mediate …

pMAT: An open-source software suite for the analysis of fiber photometry data

CA Bruno, C O'Brien, S Bryant, JI Mejaes… - Pharmacology …, 2021 - Elsevier
The combined development of new technologies for neuronal recordings and the
development of novel sensors for recording both cellular activity and neurotransmitter …

The paraventricular nucleus of the thalamus: an integrative node underlying homeostatic behavior

MA Penzo, C Gao - Trends in neurosciences, 2021 - cell.com
Early anatomical evidence suggested that the paraventricular nucleus of the thalamus (PVT)
regulates arousal, as well as emotional and motivated behaviors. We discuss recent studies …

Three-photon excited fluorescence imaging in neuroscience: From principles to applications

Y Xiao, P Deng, Y Zhao, S Yang, B Li - Frontiers in Neuroscience, 2023 - frontiersin.org
The development of three-photon microscopy (3PM) has greatly expanded the capability of
imaging deep within biological tissues, enabling neuroscientists to visualize the structure …

An ultra-compact promoter drives widespread neuronal expression in mouse and monkey brains

J Wang, J Lin, Y Chen, J Liu, Q Zheng, M Deng… - Cell Reports, 2023 - cell.com
Promoters are essential tools for basic and translational neuroscience research. An ideal
promoter should possess the shortest possible DNA sequence with cell-type selectivity …

Monitoring Astrocytic Ca2+ Activity in Freely Behaving Mice

H Qin, W He, C Yang, J Li, T Jian, S Liang… - Frontiers in Cellular …, 2020 - frontiersin.org
Monitoring astrocytic Ca2+ activity is essential to understand the physiological and
pathological roles of astrocytes in the brain. However, previous commonly used methods for …

Association of increased amygdala activity with stress-induced anxiety but not social avoidance behavior in mice

SH Huang, WZ Liu, X Qin, CY Guo, QC Xiong… - Neuroscience …, 2022 - Springer
Chronic stress leads to many psychiatric disorders, including social and anxiety disorders
that are associated with over-activation of neurons in the basolateral amygdala (BLA) …

Rodent models for psychiatric disorders: problems and promises

M Baker, SI Hong, S Kang, DS Choi - Laboratory Animal Research, 2020 - Springer
Psychiatric disorders are a prevalent global health problem, over 900 million individuals
affected by a continuum of mental and substance use disorders. Due to this high prevalence …

PhAT: A Flexible Open‐Source GUI‐Driven Toolkit for Photometry Analysis

KZ Murphy, ED Haile, AD McTigue, AF Pierce… - Current …, 2023 - Wiley Online Library
Photometry approaches detect sensor‐mediated changes in fluorescence as a proxy for
rapid molecular changes within the brain. As a flexible technique with a relatively low cost to …