Computational flow dynamic analysis in left atrial appendage thrombus formation risk: A review

S Valvez, M Oliveira-Santos, AP Piedade… - Applied Sciences, 2023 - mdpi.com
Atrial fibrillation (AF) is a common cardiac arrhythmia characterized by irregular and rapid
electrical activity in the atria, leading to ineffective contraction and poor blood flow. More …

Imaging and biophysical modelling of thrombogenic mechanisms in atrial fibrillation and stroke

A Qureshi, GYH Lip, DA Nordsletten… - Frontiers in …, 2023 - frontiersin.org
Atrial fibrillation (AF) underlies almost one third of all ischaemic strokes, with the left atrial
appendage (LAA) identified as the primary thromboembolic source. Current stroke risk …

The impact of left atrium appendage morphology on stroke risk assessment in atrial fibrillation: a computational fluid dynamics study

A Masci, L Barone, L Dedè, M Fedele, C Tomasi… - Frontiers in …, 2019 - frontiersin.org
Atrial fibrillation (AF) carries out a 5-fold increase in stroke risk, related to embolization of
thrombi clotting in left atrium (LA). Left atrial appendage (LAA) is the site with the highest …

Computational fluid dynamic analysis of the left atrial appendage to predict thrombosis risk

GM Bosi, A Cook, R Rai, LJ Menezes… - Frontiers in …, 2018 - frontiersin.org
During Atrial Fibrillation (AF) more than 90% of the left atrial thrombi responsible for
thromboembolic events originate in the left atrial appendage (LAA), a complex small sac …

Demonstration of patient-specific simulations to assess left atrial appendage thrombogenesis risk

M García-Villalba, L Rossini, A Gonzalo… - Frontiers in …, 2021 - frontiersin.org
Atrial fibrillation (AF) alters left atrial (LA) hemodynamics, which can lead to thrombosis in
the left atrial appendage (LAA), systemic embolism and stroke. A personalized risk …

Hemodynamics of the heart's left atrium based on a variational multiscale-LES numerical method

A Zingaro, F Menghini, A Quarteroni - European Journal of Mechanics-B …, 2021 - Elsevier
In this paper, we investigate the haemodynamics of a left atrium (LA) by proposing a
computational model suitable to provide physically meaningful fluid dynamics indications …

[HTML][HTML] A comprehensive comparison of various patient-specific CFD models of the left atrium for atrial fibrillation patients

J Dueñas-Pamplona, JG García… - Computers in Biology …, 2021 - Elsevier
Background Recently, advances in medical imaging, segmentation techniques, and high-
performance computing have supported the use of patient-specific computational fluid …

Impact of atrial fibrillation on left atrium haemodynamics: A computational fluid dynamics study

M Corti, A Zingaro, AM Quarteroni - Computers in Biology and Medicine, 2022 - Elsevier
We analyse the haemodynamics of the left atrium, highlighting differences between healthy
individuals and patients affected by atrial fibrillation. The computational study is based on …

[HTML][HTML] An electromechanics-driven fluid dynamics model for the simulation of the whole human heart

A Zingaro, M Bucelli, R Piersanti, F Regazzoni… - Journal of …, 2024 - Elsevier
We introduce a multiphysics and geometric multiscale computational model, suitable to
describe the hemodynamics of the whole human heart, driven by a four-chamber …

A geometric multiscale model for the numerical simulation of blood flow in the human left heart

A Zingaro, I Fumagalli, L Dede, M Fedele… - arXiv preprint arXiv …, 2021 - arxiv.org
We present a new computational model for the numerical simulation of blood flow in the
human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian …