Artificial intelligence for natural product drug discovery

MW Mullowney, KR Duncan, SS Elsayed… - Nature Reviews Drug …, 2023 - nature.com
Developments in computational omics technologies have provided new means to access
the hidden diversity of natural products, unearthing new potential for drug discovery. In …

Machine and deep learning approaches for cancer drug repurposing

NT Issa, V Stathias, S Schürer… - Seminars in cancer …, 2021 - Elsevier
Abstract Knowledge of the underpinnings of cancer initiation, progression and metastasis
has increased exponentially in recent years. Advanced “omics” coupled with machine …

The IntAct database: efficient access to fine-grained molecular interaction data

N Del Toro, A Shrivastava, E Ragueneau… - Nucleic acids …, 2022 - academic.oup.com
The IntAct molecular interaction database (https://www. ebi. ac. uk/intact) is a curated
resource of molecular interactions, derived from the scientific literature and from direct data …

The BioGRID interaction database: 2019 update

R Oughtred, C Stark, BJ Breitkreutz, J Rust… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Biological General Repository for Interaction Datasets (BioGRID:
https://thebiogrid. org) is an open access database dedicated to the curation and archival …

ChEMBL: towards direct deposition of bioassay data

D Mendez, A Gaulton, AP Bento… - Nucleic acids …, 2019 - academic.oup.com
ChEMBL is a large, open-access bioactivity database (https://www. ebi. ac. uk/chembl),
previously described in the 2012, 2014 and 2017 Nucleic Acids Research Database Issues …

The immune epitope database (IEDB): 2018 update

R Vita, S Mahajan, JA Overton, SK Dhanda… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Immune Epitope Database (IEDB, iedb. org) captures experimental data
confined in figures, text and tables of the scientific literature, making it freely available and …

Expression Atlas update: gene and protein expression in multiple species

P Moreno, S Fexova, N George… - Nucleic acids …, 2022 - academic.oup.com
Abstract The EMBL-EBI Expression Atlas is an added value knowledge base that enables
researchers to answer the question of where (tissue, organism part, developmental stage …

The ChEMBL database in 2017

A Gaulton, A Hersey, M Nowotka, AP Bento… - Nucleic acids …, 2017 - academic.oup.com
ChEMBL is an open large-scale bioactivity database (https://www. ebi. ac. uk/chembl),
previously described in the 2012 and 2014 Nucleic Acids Research Database Issues. Since …

[HTML][HTML] The cellosaurus, a cell-line knowledge resource

A Bairoch - Journal of biomolecular techniques: JBT, 2018 - ncbi.nlm.nih.gov
The Cellosaurus is a knowledge resource on cell lines. It aims to describe all cell lines used
in biomedical research. Its scope encompasses both vertebrates and invertebrates …

PubChem 2023 update

S Kim, J Chen, T Cheng, A Gindulyte, J He… - Nucleic acids …, 2023 - academic.oup.com
Abstract PubChem (https://pubchem. ncbi. nlm. nih. gov) is a popular chemical information
resource that serves a wide range of use cases. In the past two years, a number of changes …