Artificial intelligence for natural product drug discovery
MW Mullowney, KR Duncan, SS Elsayed… - Nature Reviews Drug …, 2023 - nature.com
Developments in computational omics technologies have provided new means to access
the hidden diversity of natural products, unearthing new potential for drug discovery. In …
the hidden diversity of natural products, unearthing new potential for drug discovery. In …
Machine and deep learning approaches for cancer drug repurposing
NT Issa, V Stathias, S Schürer… - Seminars in cancer …, 2021 - Elsevier
Abstract Knowledge of the underpinnings of cancer initiation, progression and metastasis
has increased exponentially in recent years. Advanced “omics” coupled with machine …
has increased exponentially in recent years. Advanced “omics” coupled with machine …
The IntAct database: efficient access to fine-grained molecular interaction data
N Del Toro, A Shrivastava, E Ragueneau… - Nucleic acids …, 2022 - academic.oup.com
The IntAct molecular interaction database (https://www. ebi. ac. uk/intact) is a curated
resource of molecular interactions, derived from the scientific literature and from direct data …
resource of molecular interactions, derived from the scientific literature and from direct data …
The BioGRID interaction database: 2019 update
R Oughtred, C Stark, BJ Breitkreutz, J Rust… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Biological General Repository for Interaction Datasets (BioGRID:
https://thebiogrid. org) is an open access database dedicated to the curation and archival …
https://thebiogrid. org) is an open access database dedicated to the curation and archival …
ChEMBL: towards direct deposition of bioassay data
D Mendez, A Gaulton, AP Bento… - Nucleic acids …, 2019 - academic.oup.com
ChEMBL is a large, open-access bioactivity database (https://www. ebi. ac. uk/chembl),
previously described in the 2012, 2014 and 2017 Nucleic Acids Research Database Issues …
previously described in the 2012, 2014 and 2017 Nucleic Acids Research Database Issues …
The immune epitope database (IEDB): 2018 update
R Vita, S Mahajan, JA Overton, SK Dhanda… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Immune Epitope Database (IEDB, iedb. org) captures experimental data
confined in figures, text and tables of the scientific literature, making it freely available and …
confined in figures, text and tables of the scientific literature, making it freely available and …
Expression Atlas update: gene and protein expression in multiple species
P Moreno, S Fexova, N George… - Nucleic acids …, 2022 - academic.oup.com
Abstract The EMBL-EBI Expression Atlas is an added value knowledge base that enables
researchers to answer the question of where (tissue, organism part, developmental stage …
researchers to answer the question of where (tissue, organism part, developmental stage …
The ChEMBL database in 2017
A Gaulton, A Hersey, M Nowotka, AP Bento… - Nucleic acids …, 2017 - academic.oup.com
ChEMBL is an open large-scale bioactivity database (https://www. ebi. ac. uk/chembl),
previously described in the 2012 and 2014 Nucleic Acids Research Database Issues. Since …
previously described in the 2012 and 2014 Nucleic Acids Research Database Issues. Since …
[HTML][HTML] The cellosaurus, a cell-line knowledge resource
A Bairoch - Journal of biomolecular techniques: JBT, 2018 - ncbi.nlm.nih.gov
The Cellosaurus is a knowledge resource on cell lines. It aims to describe all cell lines used
in biomedical research. Its scope encompasses both vertebrates and invertebrates …
in biomedical research. Its scope encompasses both vertebrates and invertebrates …
PubChem 2023 update
S Kim, J Chen, T Cheng, A Gindulyte, J He… - Nucleic acids …, 2023 - academic.oup.com
Abstract PubChem (https://pubchem. ncbi. nlm. nih. gov) is a popular chemical information
resource that serves a wide range of use cases. In the past two years, a number of changes …
resource that serves a wide range of use cases. In the past two years, a number of changes …