Melatonin as an anti-aging therapy for age-related cardiovascular and neurodegenerative diseases

VM Martín Giménez, N de Las Heras… - Frontiers in Aging …, 2022 - frontiersin.org
The concept of “aging” is defined as the set of gradual and progressive changes in an
organism that leads to an increased risk of weakness, disease, and death. This process may …

[HTML][HTML] Aging, circadian disruption and neurodegeneration: Interesting interplay

AK Verma, S Singh, SI Rizvi - Experimental Gerontology, 2023 - Elsevier
The circadian system is an intricate molecular network of coordinating circadian clocks that
organize the internal synchrony of the organism in response to the environment. These …

Acute circadian disruption due to constant light promotes Caspase 1 activation in the mouse hippocampus

P Ketelauri, K Scharov, C von Gall, S Johann - Cells, 2023 - mdpi.com
In mammals, the circadian system controls various physiological processes to maintain
metabolism, behavior, and immune function during a daily 24 h cycle. Although driven by a …

Crosstalk between aging, circadian rhythm, and melatonin

AK Verma, MI Khan, F Ashfaq, SI Rizvi - Rejuvenation Research, 2023 - liebertpub.com
Circadian rhythms (CRs) are 24-hour periodic oscillations governed by an endogenous
circadian pacemaker located in the suprachiasmatic nucleus (SCN), which organizes the …

Therapeutic potential of melatonin and its derivatives in aging and neurodegenerative diseases

AK Verma, S Singh, SI Rizvi - Biogerontology, 2023 - Springer
Aging is associated with increasing impairments in brain homeostasis and represents the
main risk factor across most neurodegenerative disorders. Melatonin, a neuroendocrine …

Association Between Outdoor Light at Night Exposure and Executive Function in Chinese Children

HY Yang, SH Wu, S Zhang, HX Zou, LB Wang… - Environmental …, 2024 - Elsevier
Background Recent evidences highlight the potential impact of outdoor Light at Night (LAN)
on executive function. However, few studies have investigated the association between …

Borolatonin limits cognitive deficit and neuron loss while increasing proBDNF in ovariectomised rats

M Barrón‐González, AM Rivera‐Antonio… - Fundamental & …, 2024 - Wiley Online Library
Background Borolatonin is a potential therapeutic agent for some neuronal diseases such
as Alzheimer's disease (AD). Its administration exerts ameliorative effects such as those …

Melatonin stabilizes age-dependent alterations in erythrocyte membrane induced by 'Artificial Light at Night'in a chronodisrupted model of rat

AK Verma, S Singh, P Srivastava, SI Rizvi - General and Comparative …, 2022 - Elsevier
Growing evidence has shown that Artificial light at night (ALAN) is one of the threatening risk
factors which disrupt circadian homeodynamics of cellular processes. The chronobiological …

[HTML][HTML] Melatonin and its physiological and therapeutic effects: A review

BV Stefanović, NM Spasojević… - Kragujevac Journal of …, 2024 - scindeks.ceon.rs
Melatonin, an evolutionarily old molecule, is found in many living organisms. This
neurohormone is known to control many physiological processes, including circadian …