The gut barrier as a gatekeeper in colorectal cancer treatment

R Hajjar, C Richard, MM Santos - Oncotarget, 2024 - pmc.ncbi.nlm.nih.gov
Colorectal cancer (CRC) is highly prevalent and is a major cause of cancer-related deaths
worldwide. The incidence rate of CRC remains alarmingly high despite screening measures …

Modulating gut microbiota prevents anastomotic leak to reduce local implantation and dissemination of colorectal cancer cells after surgery

R Hajjar, M Oliero, G Fragoso, AS Ajayi, AA Alaoui… - Clinical Cancer …, 2024 - AACR
Purpose: Anastomotic leak (AL) is a major complication in colorectal cancer surgery and
consists of the leakage of intestinal content through a poorly healed colonic wound …

[HTML][HTML] Peroxisome proliferator-activated receptor gamma (PPAR-γ) activation through gut microbiota modulation as a novel therapeutic approach against …

MÁ Núñez-Sánchez… - Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Peroxisome proliferator-activated receptor gamma (PPAR-γ) activation through gut microbiota
modulation as a novel therapeutic approach against anastomotic leak after colorectal cancer …

Gut microbiota modulation: the key to improving outcomes after colorectal cancer surgery?

JA Helliwell, DG Jayne - Journal of Gastrointestinal Oncology, 2024 - pmc.ncbi.nlm.nih.gov
© Journal of Gastrointestinal Oncology. All rights reserved. J Gastrointest Oncol 2024; 15 (4):
1993-1995| https://dx. doi. org/10.21037/jgo-24-289 poor anastomotic healing. Second, the …

[引用][C] Early detection of colonic anastomotic leak

C Paterson, AG Hill - ANZ Journal of Surgery - Wiley Online Library
Technical failure or inadequate blood flow are obvious contributors to AL. However, many
other factors can limit a patient's progress towards anastomotic healing, such as …