The emerging and powerful field of spatial pharmacology can map the spatial distribution of
drugs and their metabolites, as well as their effects on endogenous biomolecules including …

Spatial multi-omic studies have emerged as a promising approach to comprehensively
analyze cells in tissues, enabling the joint analysis of multiple data modalities like …

Spatial transcriptomics (ST) technologies enable high throughput gene expression
characterization within thin tissue sections. However, comparing spatial observations across …

Hundreds of millions of single cells have been analyzed to date using high throughput
transcriptomic methods, thanks to technological advances driving the increasingly rapid …

Kidney organoids are three-dimensional structures generated from pluripotent stem cells
(PSCs) that are capable of recapitulating the major structures of mammalian kidneys. As this …

Antigen-specific T cells traffic to, are influenced by, and create unique cellular
microenvironments. Here we characterize these microenvironments over time with …

Follicular lymphoma (FL) is a generally incurable malignancy that evolves from
developmentally blocked germinal center (GC) B cells. To promote survival and immune …

The ability to localize hundreds of macromolecules to discrete locations, structures and cell
types in a tissue is a powerful approach to understand the cellular and spatial organization …

In 1665 Robert Hooke, looking at cork through his microscope, discovered that plants are
composed of elementary structures he named “cells”. Variation in the expression of a single …

Abstract Machine Learning (ML) has become pivotal across various fields, offering
innovative solutions to complex data challenges. Professionals typically seek models that …