The Androgen Receptor (AR) is emerging as an important factor in the pathogenesis of
breast cancer (BC), which is the most common malignancy among females worldwide. The …

Transgender people comprise a diverse group of individuals whose gender identity or
expression differs from that originally assigned to them at birth. Some, but not all …

Androgen receptor (AR) signaling exerts an antiestrogenic, growth-inhibitory influence in
normal breast tissue, and this role may be sustained in estrogen receptor α (ERα)-positive …

Breast cancer and prostate cancer are the two most common invasive cancers in women
and men, respectively. Although these cancers arise in organs that are different in terms of …

A major achievement from 500 million years of evolution is the establishment of a high
secretion rate of dehydroepiandrosterone (DHEA) by the human adrenal glands coupled …

Animal models of cancer have been instrumental in advancing our understanding of the
biology of tumor initiation and progression, in studying gene function and in performing …

Androgens have important physiological effects in women. Postmenopausal androgen
replacement, most commonly as testosterone therapy, is becoming increasingly widespread …

Androgens have important physiological effects in women while at the same time they may
be implicated in breast cancer pathologies. However, data on the effects of androgens on …

Objective: Because the exclusive source of sex steroids (at least estrogens) after
menopause is recognized to be dehydroepiandrosterone (DHEA), this study examines the …

Salivary duct carcinoma (SDC), a rare malignancy, manifests remarkable morphologic and
biologic resemblance to high-grade mammary ductal carcinoma. We contend that, similar to …