Updated review of advances in microRNAs and complex diseases: taxonomy, trends and challenges of computational models

L Huang, L Zhang, X Chen - Briefings in bioinformatics, 2022 - academic.oup.com
Since the problem proposed in late 2000s, microRNA–disease association (MDA)
predictions have been implemented based on the data fusion paradigm. Integrating diverse …

Updated review of advances in microRNAs and complex diseases: towards systematic evaluation of computational models

L Huang, L Zhang, X Chen - Briefings in bioinformatics, 2022 - academic.oup.com
Currently, there exist no generally accepted strategies of evaluating computational models
for microRNA-disease associations (MDAs). Though K-fold cross validations and case …

MDHGI: matrix decomposition and heterogeneous graph inference for miRNA-disease association prediction

X Chen, J Yin, J Qu, L Huang - PLoS computational biology, 2018 - journals.plos.org
Recently, a growing number of biological research and scientific experiments have
demonstrated that microRNA (miRNA) affects the development of human complex diseases …

Predicting miRNA–disease associations via learning multimodal networks and fusing mixed neighborhood information

Z Lou, Z Cheng, H Li, Z Teng, Y Liu… - Briefings in …, 2022 - academic.oup.com
Motivation In recent years, a large number of biological experiments have strongly shown
that miRNAs play an important role in understanding disease pathogenesis. The discovery …

iCircDA-MF: identification of circRNA-disease associations based on matrix factorization

H Wei, B Liu - Briefings in bioinformatics, 2020 - academic.oup.com
Circular RNAs (circRNAs) are a group of novel discovered non-coding RNAs with closed-
loop structure, which play critical roles in various biological processes. Identifying …

MDA-GCNFTG: identifying miRNA-disease associations based on graph convolutional networks via graph sampling through the feature and topology graph

Y Chu, X Wang, Q Dai, Y Wang, Q Wang… - Briefings in …, 2021 - academic.oup.com
Accurate identification of the miRNA-disease associations (MDAs) helps to understand the
etiology and mechanisms of various diseases. However, the experimental methods are …

AEMDA: inferring miRNA–disease associations based on deep autoencoder

C Ji, Z Gao, X Ma, Q Wu, J Ni, C Zheng - Bioinformatics, 2021 - academic.oup.com
Motivation MicroRNAs (miRNAs) are a class of non-coding RNAs that play critical roles in
various biological processes. Many studies have shown that miRNAs are closely related to …

Impact of categorical and numerical features in ensemble machine learning frameworks for heart disease prediction

C Pan, A Poddar, R Mukherjee, AK Ray - Biomedical Signal Processing …, 2022 - Elsevier
Cardiovascular disease (CVD) or heart disease is one of the most fatal diseases of the world
that has been observed through-out the last decade. The prediction of CVD in majority of …

MDA-CF: predicting miRNA-disease associations based on a cascade forest model by fusing multi-source information

Q Dai, Y Chu, Z Li, Y Zhao, X Mao, Y Wang… - Computers in Biology …, 2021 - Elsevier
MicroRNAs (miRNAs) are significant regulators in various biological processes. They may
become promising biomarkers or therapeutic targets, which provide a new perspective in …

Research progress of miRNA–disease association prediction and comparison of related algorithms

L Yu, Y Zheng, B Ju, C Ao, L Gao - Briefings in Bioinformatics, 2022 - academic.oup.com
With an in-depth understanding of noncoding ribonucleic acid (RNA), many studies have
shown that microRNA (miRNA) plays an important role in human diseases. Because …