Tuberculosis (TB) is a major infectious disease killing nearly two million people, mostly in
developing countries, every year. The increasing incidence of resistance of Mycobacterium …

With nearly 9 million new active disease cases and 2 million deaths occurring worldwide
every year, tuberculosis continues to remain a major public health problem. Exposure to …

Touchdown (TD) PCR offers a simple and rapid means to optimize PCRs, increasing
specificity, sensitivity and yield, without the need for lengthy optimizations and/or the …

Mycobacterium tuberculosis is one of the leading causes of death worldwide, and multidrug-
resistant tuberculosis (MDR-TB) is associated with a high case fatality rate. Rapid …

Background Accurate drug susceptibility testing (DST) of Mycobacterium tuberculosis in
clinical specimens and culture isolates to first-line drugs is crucial for diagnosis and …

Objectives To characterize 250 drug-resistant Mycobacterium tuberculosis (MTB) isolates in
Hong Kong with respect to their drug susceptibility phenotypes to five common anti …

SETTING: Recent reports of embB306 mutations in ethambutol-resistant and ethambutol-
susceptible drug-resistant strains of Mycobacterium tuberculosis have questioned the …

Abstract Background Multidrug-resistant (MDR) Mycobacterium tuberculosis poses a serious
threat to the control of tuberculosis (TB) and constitutes an increasing public health problem …

The distribution and resistance levels of 189 in vitro-selected rifampin-resistant
Mycobacterium tuberculosis mutants of Beijing and other genotypes were determined. Apart …

Background Increasing incidence of multidrug-resistant Mycobacterium tuberculosis
infections is hampering global tuberculosis control efforts. Kuwait is a low-tuberculosis …