Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches
K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …
therapy, currently, there is no significant progress in the treatment of different types of brain …
Non-ionic surfactants for stabilization of polymeric nanoparticles for biomedical uses
H Cortés, H Hernández-Parra, SA Bernal-Chávez… - Materials, 2021 - mdpi.com
Surfactants are essential in the manufacture of polymeric nanoparticles by emulsion
formation methods and to preserve the stability of carriers in liquid media. The deposition of …
formation methods and to preserve the stability of carriers in liquid media. The deposition of …
Small interfering RNA (siRNA) to target genes and molecular pathways in glioblastoma therapy: Current status with an emphasis on delivery systems
Glioblastoma multiforme (GBM) is one of the worst brain tumors arising from glial cells,
causing many deaths annually. Surgery, chemotherapy, radiotherapy and immunotherapy …
causing many deaths annually. Surgery, chemotherapy, radiotherapy and immunotherapy …
Polymeric nanoparticles—Tools in a drug delivery system in selected cancer therapies
M Madej, N Kurowska, B Strzalka-Mrozik - Applied Sciences, 2022 - mdpi.com
The increase in cancer cases is undoubtedly affecting the development of new therapeutic
approaches. Polymeric nanoparticles are of great interest. Due to their relatively small size …
approaches. Polymeric nanoparticles are of great interest. Due to their relatively small size …
[HTML][HTML] Biodegradable gellan gum hydrogels loaded with paclitaxel for HER2+ breast cancer local therapy
Hydrogels loaded with chemotherapeutics are promising tools for local tumor treatment. In
this work, redox-responsive implantable hydrogels based on gellan gum were prepared as …
this work, redox-responsive implantable hydrogels based on gellan gum were prepared as …
Emerging strategies to fabricate polymeric nanocarriers for enhanced drug delivery across blood-brain barrier: An overview
Blood-brain barrier (BBB) serves as an essential interface between central nervous system
(CNS) and its periphery, allowing selective permeation of ions, gaseous molecules, and …
(CNS) and its periphery, allowing selective permeation of ions, gaseous molecules, and …
Polymeric nanoparticles for drug delivery in glioblastoma: State of the art and future perspectives
Glioblastoma (GBM) is an aggressive, fatal and malignant primary brain tumor. Despite the
current standard treatment for glioblastoma patients including neurosurgical resection …
current standard treatment for glioblastoma patients including neurosurgical resection …
Nose to Brain Delivery of Transferrin conjugated PLGA nanoparticles for clonidine
The present work focuses on the development of surface modified transferrin PLGA
nanoparticles loaded with clonidine for nose to brain delivery. The CLD-Tf-PLGA-NPs were …
nanoparticles loaded with clonidine for nose to brain delivery. The CLD-Tf-PLGA-NPs were …
Improving temozolomide biopharmaceutical properties in glioblastoma multiforme (GBM) treatment using GBM-targeting nanocarriers
Glioblastoma multiforme (GBM) is the most common primary brain cancer. GBM has
aggressive development, and the pharmacological treatment remains a challenge due to …
aggressive development, and the pharmacological treatment remains a challenge due to …
Biosynthesis of iron nanoparticles using brown algae Spatoglossum asperum and its antioxidant and anticancer activities through in vitro and in silico studies
T Palaniyandi, G Baskar, BV… - Particulate Science …, 2023 - Taylor & Francis
Green synthesized metal nanoparticles play a significant role in biomedical applications.
This investigation focused on eco-friendly synthesized iron nanoparticles using marine …
This investigation focused on eco-friendly synthesized iron nanoparticles using marine …