Innovations in genomic antimicrobial resistance surveillance

NE Wheeler, V Price, E Cunningham-Oakes… - The Lancet …, 2023 - thelancet.com
Whole-genome sequencing of antimicrobial-resistant pathogens is increasingly being used
for antimicrobial resistance (AMR) surveillance, particularly in high-income countries …

Using machine learning to predict antimicrobial resistance―a literature review

A Sakagianni, C Koufopoulou, G Feretzakis, D Kalles… - Antibiotics, 2023 - mdpi.com
Machine learning (ML) algorithms are increasingly applied in medical research and in
healthcare, gradually improving clinical practice. Among various applications of these novel …

The burden of bacterial antimicrobial resistance in the WHO African region in 2019: a cross-country systematic analysis

B Sartorius, AP Gray, ND Weaver, GR Aguilar… - The Lancet Global …, 2024 - thelancet.com
Background A critical and persistent challenge to global health and modern health care is
the threat of antimicrobial resistance (AMR). Previous studies have reported a …

Next-generation sequencing and PCR technologies in monitoring the hospital microbiome and its drug resistance

C Cason, M D'Accolti, I Soffritti, S Mazzacane… - Frontiers in …, 2022 - frontiersin.org
The hospital environment significantly contributes to the onset of healthcare-associated
infections (HAIs), which represent one of the most frequent complications occurring in …

Antimicrobial stewardship in the hospital setting: a narrative review

H Giamarellou, L Galani, T Karavasilis, K Ioannidis… - Antibiotics, 2023 - mdpi.com
The increasing global threat of antibiotic resistance, which has resulted in countless fatalities
due to untreatable infections, underscores the urgent need for a strategic action plan. The …

A comprehensive review on genomics, systems biology and structural biology approaches for combating antimicrobial resistance in ESKAPE pathogens …

P Priyamvada, R Debroy, A Anbarasu… - World Journal of …, 2022 - Springer
In recent decades, antimicrobial resistance has been augmented as a global concern to
public health owing to the global spread of multidrug-resistant strains from different ESKAPE …

Global pathogenomic analysis identifies known and candidate genetic antimicrobial resistance determinants in twelve species

JC Hyun, JM Monk, R Szubin, Y Hefner… - Nature …, 2023 - nature.com
Surveillance programs for managing antimicrobial resistance (AMR) have yielded
thousands of genomes suited for data-driven mechanism discovery. We present a workflow …

Enterococcus species: insights into antimicrobial resistance and whole-genome features of isolates recovered from livestock and raw meat in Ghana

GR Amuasi, E Dsani, C Owusu-Nyantakyi… - Frontiers in …, 2023 - frontiersin.org
Introduction Enterococcus spp. have gradually evolved from commensals to causing life-
threatening hospital-acquired infections globally due to their inherent antimicrobial …

Genomic analysis of almost 8,000 Salmonella genomes reveals drivers and landscape of antimicrobial resistance in China

Y Wang, X Xu, B Zhu, N Lyu, Y Liu, S Ma… - Microbiology …, 2023 - Am Soc Microbiol
Foodborne Salmonella infection remains a major public health concern worldwide. With
rising antimicrobial resistance, genomic surveillance is key to tracking outbreaks and …

Factors associated with plasmid antibiotic resistance gene carriage revealed using large-scale multivariable analysis

A Orlek, MF Anjum, AE Mather, N Stoesser… - Scientific Reports, 2023 - nature.com
Plasmids are major vectors of bacterial antibiotic resistance, but understanding of factors
associated with plasmid antibiotic resistance gene (ARG) carriage is limited. We curated> …