Targeting inflammation in the treatment of type 2 diabetes: time to start
MY Donath - Nature reviews Drug discovery, 2014 - nature.com
The role of inflammation in the pathogenesis of type 2 diabetes and associated
complications is now well established. Several conditions that are driven by inflammatory …
complications is now well established. Several conditions that are driven by inflammatory …
[HTML][HTML] The cardio-renal-metabolic connection: a review of the evidence
M Marassi, GP Fadini - Cardiovascular Diabetology, 2023 - Springer
Abstract Type 2 diabetes (T2D), cardiovascular disease (CVD) and chronic kidney disease
(CKD), are recognized among the most disruptive public health issues of the current century …
(CKD), are recognized among the most disruptive public health issues of the current century …
[HTML][HTML] Blood pressure lowering and risk of new-onset type 2 diabetes: an individual participant data meta-analysis
Background Blood pressure lowering is an established strategy for preventing microvascular
and macrovascular complications of diabetes, but its role in the prevention of diabetes itself …
and macrovascular complications of diabetes, but its role in the prevention of diabetes itself …
[HTML][HTML] Potential metabolic and inflammatory pathways between COVID-19 and new-onset diabetes
The pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is rapidly evolving worldwide and is now face-to …
syndrome coronavirus 2 (SARS-CoV-2), is rapidly evolving worldwide and is now face-to …
Obesity‐related hypertension: Pathogenesis, cardiovascular risk, and treatment—A position paper of the The Obesity Society and the American Society of …
In light of the worldwide epidemic of obesity, and in recognition of hypertension as a major
factor in the cardiovascular morbidity and mortality associated with obesity, The Obesity …
factor in the cardiovascular morbidity and mortality associated with obesity, The Obesity …
[HTML][HTML] Obesity, metabolic syndrome, and primary hypertension
M Litwin, Z Kułaga - Pediatric Nephrology, 2021 - Springer
Primary hypertension is the dominant form of arterial hypertension in adolescents. Disturbed
body composition with, among other things, increased visceral fat deposition, accelerated …
body composition with, among other things, increased visceral fat deposition, accelerated …
Diabetic cardiomyopathy: mechanisms and new treatment strategies targeting antioxidant signaling pathways
K Huynh, BC Bernardo, JR McMullen… - Pharmacology & …, 2014 - Elsevier
Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …
population. Both experimental and clinical evidence suggest that diabetic subjects are …
[HTML][HTML] The role of leptin/adiponectin ratio in metabolic syndrome and diabetes
P López-Jaramillo, D Gómez-Arbeláez… - … molecular biology and …, 2014 - degruyter.com
The metabolic syndrome comprises a cluster of cardiometabolic risk factors, with insulin
resistance and adiposity as its central features. Identifying individuals with metabolic …
resistance and adiposity as its central features. Identifying individuals with metabolic …
Anti-inflammatory agents in the treatment of diabetes and its vascular complications
RM Pollack, MY Donath, D LeRoith… - Diabetes care, 2016 - Am Diabetes Assoc
The association between hyperglycemia and inflammation and vascular complications in
diabetes is now well established. Antidiabetes drugs may alleviate inflammation by reducing …
diabetes is now well established. Antidiabetes drugs may alleviate inflammation by reducing …
[HTML][HTML] Effect of valsartan on the incidence of diabetes and cardiovascular events
NAVIGATOR Study Group - New England Journal of Medicine, 2010 - Mass Medical Soc
Background It is not known whether drugs that block the renin–angiotensin system reduce
the risk of diabetes and cardiovascular events in patients with impaired glucose tolerance …
the risk of diabetes and cardiovascular events in patients with impaired glucose tolerance …