Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management

SYC Tong, JS Davis, E Eichenberger… - Clinical microbiology …, 2015 - Am Soc Microbiol
Staphylococcus aureus is a major human pathogen that causes a wide range of clinical
infections. It is a leading cause of bacteremia and infective endocarditis as well as …

Biofilms in periprosthetic orthopedic infections

SJ McConoughey, R Howlin, JF Granger… - Future …, 2014 - Taylor & Francis
As the number of total joint arthroplasty and internal fixation procedures continues to rise,
the threat of infection following surgery has significant clinical implications. These infections …

[HTML][HTML] Recent evidence on bioactive glass antimicrobial and antibiofilm activity: a mini-review

L Drago, M Toscano, M Bottagisio - Materials, 2018 - mdpi.com
Bone defects caused by trauma or pathological events are major clinical and socioeconomic
burdens. Thus, the efforts of regenerative medicine have been focused on the development …

[HTML][HTML] Time trends in the aetiology of prosthetic joint infections: a multicentre cohort study

N Benito, M Franco, A Ribera, A Soriano… - Clinical Microbiology …, 2016 - Elsevier
It is important to know the spectrum of the microbial aetiology of prosthetic joint infections
(PJIs) to guide empiric treatment and establish antimicrobial prophylaxis in joint …

[HTML][HTML] Culture-negative periprosthetic joint infections

J Palan, C Nolan, K Sarantos… - EFORT open …, 2019 - eor.bioscientifica.com
Culture-negative periprosthetic joint infections (CN-PJI) pose a significant challenge in terms
of diagnosis and management. The reported incidence of CN-PJI is reported to be between …

In vitro Antibiofilm Activity of Bioactive Glass S53P4

L Drago, C Vassena, S Fenu, ED Vecchi… - Future …, 2014 - Taylor & Francis
Aim: This work aimed to investigate the ability of different formulations of bioactive glass
(BAG)-S53P4 to interfere with bacterial biofilm produced on prosthetic material by methicillin …

[HTML][HTML] The role of WNT and IL-1 signaling in osteoarthritis: therapeutic implications for platelet-rich plasma therapy

A Tonutti, V Granata, V Marrella, C Sobacchi… - Frontiers in …, 2023 - frontiersin.org
Different from inflammatory arthritis, where biologicals and targeted synthetic molecules
have revolutionized the disease course, no drug has demonstrated a disease modifying …

[HTML][HTML] Therapeutic cyclic lipopeptides mining from microbes: latest strides and hurdles

S Patel, S Ahmed, JS Eswari - World Journal of Microbiology and …, 2015 - Springer
Infectious diseases impose serious public health burdens and often have devastating
consequences. The cyclic lipopeptides elaborated by bacteria Bacillus, Paenibacillus …

[HTML][HTML] A comprehensive review of the diagnosis and management of prosthetic joint infections in the absence of positive cultures

MS Parikh, S Antony - Journal of infection and public health, 2016 - Elsevier
The diagnosis and management of prosthetic joint infections (PJI) with negative cultures
remains an enigma without clear definitions and guidelines for its management. In contrast …

Infection risk after orthopedic surgery in patients with inflammatory rheumatic diseases treated with immunosuppressive drugs

CB Scherrer, AF Mannion, D Kyburz… - Arthritis care & …, 2013 - Wiley Online Library
Objective The influence of specific medications on the risk of postoperative infection in
patients with rheumatoid arthritis and other inflammatory rheumatic diseases (IRDs) remains …